ID   A0A0N4WMT8_HAEPC        Unreviewed;       496 AA.
AC   A0A0N4WMT8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Tnf receptor-associated factor {ECO:0000313|WBParaSite:HPLM_0001254601-mRNA-1};
GN   ORFNames=HPLM_LOCUS12542 {ECO:0000313|EMBL:VDO45982.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001254601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001254601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO45982.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO45982.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; UZAF01017898; VDO45982.1; -; Genomic_DNA.
DR   STRING; 6290.A0A0N4WMT8; -.
DR   WBParaSite; HPLM_0001254601-mRNA-1; HPLM_0001254601-mRNA-1; HPLM_0001254601.
DR   OMA; HHESCLA; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR   InterPro; IPR002083; MATH/TRAF_dom.
DR   InterPro; IPR008974; TRAF-like.
DR   InterPro; IPR049342; TRAF_MEP1_MATH_dom.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   InterPro; IPR001293; Znf_TRAF.
DR   PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR   PANTHER; PTHR10131:SF151; TNF RECEPTOR ASSOCIATED FACTOR (TRAF) HOMOLOG; 1.
DR   Pfam; PF21355; TRAF-mep_MATH; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   Pfam; PF02176; zf-TRAF; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF49599; TRAF domain-like; 2.
DR   PROSITE; PS50144; MATH; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50145; ZF_TRAF; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00207}.
FT   DOMAIN          77..117
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50145"
FT   DOMAIN          129..174
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50145"
FT   DOMAIN          216..365
FT                   /note="MATH"
FT                   /evidence="ECO:0000259|PROSITE:PS50144"
FT   ZN_FING         77..117
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT   ZN_FING         129..174
FT                   /note="TRAF-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT   REGION          378..496
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        378..431
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..496
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   496 AA;  55787 MW;  B0E70CFEFF96409F CRC64;
     ALRAPVIAQC GHCFCKECID SSENWPVHCP ACGEDIAPDS LKPDNAKWRE VQSLLVDCPF
     ARNGCQWCGT LKEMQKHADS CLYHGVPCPN CKKTVPERDM ATHLEECEKK IGKCTYCGIR
     LKATGMEKHL KICPRVIMSC PFQCGLLDRT REEIEQHRPL CPNIDKFCPF AELGSLFAGD
     KETIPQHLAE EPVHHLMFLC DAITDLKAIT ANEMYGAQLI WRIDNMEQKM NEARSGTRPI
     IHSDPFVSGR YGYKFVASAC LFGDGQYRGK YMAVYVTLVR GKYDSLLQWP FDLTVCITLL
     DQNPIYENRC DISYRVDARK IKDKCEFLER PMTDRNGSFG AQTFCRLAVM DNFIREDTMF
     LKIEIDVLKS HEHLLRPTSV ANPNSTSAIN ELPPRTPVTV SQSQLPETTE EMNLGAETPS
     EPSTTLPSEE SLERPATVKE SAPNSPISPR SAAVPIIVNE ENEIQENGEI EKSHSSTAPE
     EAIDHPEVGT VRHEHE
//