ID A0A0N4WX20_HAEPC Unreviewed; 505 AA.
AC A0A0N4WX20;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Beta-galactosidase {ECO:0000313|WBParaSite:HPLM_0001633401-mRNA-1};
GN ORFNames=HPLM_LOCUS16326 {ECO:0000313|EMBL:VDO59510.1};
OS Haemonchus placei (Barber's pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001633401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HPLM_0001633401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO59510.1, ECO:0000313|Proteomes:UP000268014}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHpl1 {ECO:0000313|EMBL:VDO59510.1,
RC ECO:0000313|Proteomes:UP000268014};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
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DR EMBL; UZAF01019370; VDO59510.1; -; Genomic_DNA.
DR STRING; 6290.A0A0N4WX20; -.
DR WBParaSite; HPLM_0001633401-mRNA-1; HPLM_0001633401-mRNA-1; HPLM_0001633401.
DR OMA; FHETYKN; -.
DR Proteomes; UP000038042; Unplaced.
DR Proteomes; UP000268014; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 2.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..505
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041080349"
FT DOMAIN 33..237
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 249..288
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 291..393
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 423..474
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
SQ SEQUENCE 505 AA; 57460 MW; 8C86C88875EECBB9 CRC64;
MTSCLHSLWP LLAFGLTYVS TQRSFSIDHD NNQFLRDGKP YRYISGSIHY FRTHPDQWET
RLQTVRAAGL NSIETYIPWN FHETYKNKYD FSGMRNFSRF FELAAQNELA VIVRPGPYIC
GEWENGGLPY WLLKYPNITQ RSSDPNFLRE SLAWWDVLLP MIRPYLWQNN GPVIMIQIEN
EYGSFGCDHV YLRALRDKAI EKLGNDSVLF TTDPPETIEC GVIDGVYATV DFGERGLILA
DDYFKIQDDA NKKILELTEK LYNMNASFNY YMFHGGTNFG FWNGAEYAAG LDQPMGFVKY
SVHLNVGGSV LDCSGVRDFG YVFVNKQFRG RVSPHYKPHE VKELQLSLKR NDLLEIVVEN
QGRLTWETIN DYKGIVNPVK LDGAQLTGWT SCAVDVEQLV DVTAQSSVSS VFNVGDVFRG
DLTPTGKGDT FIDMSNWGKG VAWLNGFNLG RYWASAGPQK YLYVPAPLIT TGKNSLVFLE
LEKLSSDCKG TQCSINLLDH PLLYK
//
