ID   A0A0N4X3S6_HAEPC        Unreviewed;       156 AA.
AC   A0A0N4X3S6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=GLOBIN domain-containing protein {ECO:0000313|WBParaSite:HPLM_0001901801-mRNA-1};
GN   ORFNames=HPLM_LOCUS19010 {ECO:0000313|EMBL:VDO74511.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0001901801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0001901801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO74511.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO74511.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the globin family.
CC       {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238,
CC       ECO:0000256|RuleBase:RU000356}.
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DR   EMBL; UZAF01020986; VDO74511.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4X3S6; -.
DR   WBParaSite; HPLM_0001901801-mRNA-1; HPLM_0001901801-mRNA-1; HPLM_0001901801.
DR   OMA; MQNGKDF; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   CDD; cd01040; Mb-like; 1.
DR   Gene3D; 1.10.490.10; Globins; 1.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR012292; Globin/Proto.
DR   InterPro; IPR012085; Globin_nematode.
DR   InterPro; IPR044399; Mb-like_M.
DR   PANTHER; PTHR46458; BLR2807 PROTEIN; 1.
DR   PANTHER; PTHR46458:SF19; NEUROGLOBIN; 1.
DR   Pfam; PF00042; Globin; 1.
DR   PIRSF; PIRSF002026; Nematode_globin; 1.
DR   SUPFAM; SSF46458; Globin-like; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000356};
KW   Iron {ECO:0000256|PIRSR:PIRSR002026-1};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR002026-1};
KW   Oxygen transport {ECO:0000256|RuleBase:RU000356};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Transport {ECO:0000256|RuleBase:RU000356}.
FT   DOMAIN          27..136
FT                   /note="Globin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS01033"
FT   BINDING         97
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR002026-1"
SQ   SEQUENCE   156 AA;  17915 MW;  E2F488351C5984B5 CRC64;
     MADVKKHCIE SLKTVPLGKD PAQMQNGKDF YKYLFTNHPD LRKYFKGAEN FTADDVQKSA
     RFEKQGTSLL LSVHLLANTF DNEMLFRAFC RETLDRHVGR GLDPSLYKVF WDVWMAFLES
     RGTQLTADQK AAWGKLGAMF NEECQLQLAK HGLPHL
//