ID   A0A0N4X6K9_HAEPC        Unreviewed;       622 AA.
AC   A0A0N4X6K9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=RING-type domain-containing protein {ECO:0000313|WBParaSite:HPLM_0002000101-mRNA-1};
GN   ORFNames=HPLM_LOCUS19993 {ECO:0000313|EMBL:VDO80784.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0002000101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0002000101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO80784.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO80784.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAF01021760; VDO80784.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4X6K9; -.
DR   STRING; 6290.A0A0N4X6K9; -.
DR   WBParaSite; HPLM_0002000101-mRNA-1; HPLM_0002000101-mRNA-1; HPLM_0002000101.
DR   OMA; QVHTRAT; -.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR16079:SF4; E3 UBIQUITIN-PROTEIN LIGASE CHFR; 1.
DR   PANTHER; PTHR16079; UBIQUITIN LIGASE PROTEIN CHFR; 1.
DR   Pfam; PF13923; zf-C3HC4_2; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          75..116
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          172..252
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          268..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          312..541
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..232
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..426
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        438..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        521..541
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   622 AA;  68659 MW;  A4EB04CCE31C93E3 CRC64;
     MVRDFQLKVP STPILTGRSP IGYTTNERRK RFHSASVQVD VGSPRQRFSS EQESEQESNP
     LDIWMSSSLG ERLSCSICCE IFYKAANVIP CGHNFCLSCI MRFMATKADA ECPQCRERIK
     DIGMAYTVNS IVDVLLEKDP DKKRTAEELQ REDDMFAKAV IELRNKNRFF PRVAPPRSST
     FPQVPTREPL QLRSLSQEPA RPRTPQRRTV SQVSRQESSR IRSPSQGPIG RQVHTRATRE
     PSLPPIGSLG ATVDLSLGTL PQVSTRLILR PHARTSESSS GSSESMYSQA MAQLNTSELM
     FSQAMARLQD LSRRVQQLQQ SSPTRGTTRQ EHSSRVSTRP QVSLPLRSTS QAASSTAHRS
     ARSSTSTSLP QTLARESRVE STVTGRSPRA RIDGRGPSRL ESPRGTTRLQ TSQESTRPQA
     VTGSSPRARI DSRGPSRLES PRGTTRLQTS SQESTRPQVP LQLSSTSQVA SSINQRSTIS
     SASTSRIQIS ALGSRVEQAA SGRSPRARIH GRGPPQLQSP REARPETSQE SLRPQVPSRL
     SSTAQVASSR IHTSTRYHAT SLCPLCSARE SRVEPVSTGR SPRAPISIRA SSRLQFQTRG
     ATTTTTASSL PRVSTVRRMW RI
//