ID   A0A0N4X8U1_HAEPC        Unreviewed;       341 AA.
AC   A0A0N4X8U1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=TIL domain-containing protein {ECO:0000313|WBParaSite:HPLM_0002078301-mRNA-1};
GN   ORFNames=HPLM_LOCUS20775 {ECO:0000313|EMBL:VDO85928.1};
OS   Haemonchus placei (Barber's pole worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX   NCBI_TaxID=6290 {ECO:0000313|Proteomes:UP000038042, ECO:0000313|WBParaSite:HPLM_0002078301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:HPLM_0002078301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO85928.1, ECO:0000313|Proteomes:UP000268014}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHpl1 {ECO:0000313|EMBL:VDO85928.1,
RC   ECO:0000313|Proteomes:UP000268014};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAF01022568; VDO85928.1; -; Genomic_DNA.
DR   STRING; 6290.A0A0N4X8U1; -.
DR   WBParaSite; HPLM_0002078301-mRNA-1; HPLM_0002078301-mRNA-1; HPLM_0002078301.
DR   Proteomes; UP000038042; Unplaced.
DR   Proteomes; UP000268014; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   CDD; cd19941; TIL; 3.
DR   Gene3D; 2.10.25.10; Laminin; 3.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   PANTHER; PTHR23259; RIDDLE; 1.
DR   PANTHER; PTHR23259:SF77; TIL DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF01826; TIL; 3.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 3.
PE   4: Predicted;
KW   Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW   Reference proteome {ECO:0000313|Proteomes:UP000268014};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}.
FT   DOMAIN          21..70
FT                   /note="TIL"
FT                   /evidence="ECO:0000259|Pfam:PF01826"
FT   DOMAIN          93..142
FT                   /note="TIL"
FT                   /evidence="ECO:0000259|Pfam:PF01826"
FT   DOMAIN          155..208
FT                   /note="TIL"
FT                   /evidence="ECO:0000259|Pfam:PF01826"
FT   REGION          231..257
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..255
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   341 AA;  36728 MW;  324FCC625B2731D6 CRC64;
     QHFVKLLLIA EPSPASNNRT CPANEEFKEC GTACEPSCRN PNPVLCTEQC VIGCQCRSGF
     YRNDQNVCVS TFDDMGIASN PIKQATVVKK VTCPANEEFK ECGTACEPSC RRPNPGICTL
     QCVVGCQCKS GFYRNDENVC VANCSAPNSI GTGGCGVNEE RKQCGTACEP TCAQPNPTCT
     RQCIPDVCQC RQLYIRDSNN VCVPKASCPT GVLLNTSDVC GRIFRGKKDK RVKTIDPHAI
     GXPPPPPPPP PPGTLSQSRK VVSNAHLANS MACSGQPMRK SRLLSSHASL VPINRLRSNG
     RLGYLGWMLI RDSNRGPCLC YSGPPLRKFG EPNLLTGFSS G
//