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Database: UniProt
Entry: A0A0N4XFM7_NIPBR
LinkDB: A0A0N4XFM7_NIPBR
Original site: A0A0N4XFM7_NIPBR 
ID   A0A0N4XFM7_NIPBR        Unreviewed;       125 AA.
AC   A0A0N4XFM7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   31-JUL-2019, entry version 14.
DE   RecName: Full=IRK domain-containing protein {ECO:0000259|Pfam:PF01007};
GN   ORFNames=NBR_LOCUS1330 {ECO:0000313|EMBL:VDL64709.1};
OS   Nippostrongylus brasiliensis (Rat hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Strongylida;
OC   Trichostrongyloidea; Heligmonellidae; Nippostrongylinae;
OC   Nippostrongylus.
OX   NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000132901-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000132901-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:NBR_0000132901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:VDL64709.1, ECO:0000313|Proteomes:UP000271162}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
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DR   EMBL; UYSL01001004; VDL64709.1; -; Genomic_DNA.
DR   WBParaSite; NBR_0000132901-mRNA-1; NBR_0000132901-mRNA-1; NBR_0000132901.
DR   Proteomes; UP000038043; Genome assembly.
DR   Proteomes; UP000271162; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000038043,
KW   ECO:0000313|Proteomes:UP000271162};
KW   Ion channel {ECO:0000256|RuleBase:RU003822};
KW   Ion transport {ECO:0000256|RuleBase:RU003822};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822}.
FT   TRANSMEM     65     87       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       29    125       IRK. {ECO:0000259|Pfam:PF01007}.
SQ   SEQUENCE   125 AA;  14529 MW;  4660042CEF7F988B CRC64;
     MDETERLSCD DVRKELNGWA SAPRRARLVS KTGQTLLTSV ELPQRFRATY KNWFHLIIEC
     NWRSIIVVFA SGFIGSWTFF GTLYYLFTVV GYQTSERNCI ENVNSFVTAF LFSMESQHTI
     GYGFR
//
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