ID A0A0N4XM73_NIPBR Unreviewed; 181 AA.
AC A0A0N4XM73;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Probable tyrosine-protein phosphatase (inferred by orthology to a C. elegans protein) {ECO:0000313|WBParaSite:NBR_0000362501-mRNA-1};
GN ORFNames=NBR_LOCUS3626 {ECO:0000313|EMBL:VDL67215.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000362501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0000362501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL67215.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01005648; VDL67215.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4XM73; -.
DR STRING; 27835.A0A0N4XM73; -.
DR WBParaSite; NBR_0000362501-mRNA-1; NBR_0000362501-mRNA-1; NBR_0000362501.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR10367; MRNA-CAPPING ENZYME; 1.
DR PANTHER; PTHR10367:SF9; RNA_RNP COMPLEX-1-INTERACTING PHOSPHATASE; 1.
DR Pfam; PF00782; DSPc; 1.
DR SMART; SM00195; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162}.
FT DOMAIN 1..139
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 55..124
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 181 AA; 21067 MW; 63252A76CFE97C32 CRC64;
MSLQLAERGL RLGMVVDLTD TDRYYDKAEI EGMCIQYRKI NCPGRGFVDR TECVAEFNKA
IQDYIDRSDD EEALIGVHCT NGVNRSGYLI CRFLIERLGW SSHEALDAFE RARGYPIEKG
SYVQALHKAA IESRNRRLVM LYNFLCVNQR YCTLRVSVLL LTLLNVTYSR RAFFTRCYIR
H
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