ID A0A0N4XXM8_NIPBR Unreviewed; 1211 AA.
AC A0A0N4XXM8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Transportin-3 (inferred by orthology to a human protein) {ECO:0000313|WBParaSite:NBR_0000776101-mRNA-1};
GN ORFNames=NBR_LOCUS7762 {ECO:0000313|EMBL:VDL71351.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000776101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0000776101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL71351.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01019924; VDL71351.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4XXM8; -.
DR STRING; 27835.A0A0N4XXM8; -.
DR WBParaSite; NBR_0000776101-mRNA-1; NBR_0000776101-mRNA-1; NBR_0000776101.
DR OMA; NFWEQIY; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:UniProt.
DR CDD; cd20264; Complex1_LYR_LYRM4; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015877; Cdk-activating_kinase_MAT1_cen.
DR InterPro; IPR008011; Complex1_LYR_dom.
DR InterPro; IPR045297; Complex1_LYR_LYRM4.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12363; TRANSPORTIN 3 AND IMPORTIN 13; 1.
DR PANTHER; PTHR12363:SF33; TRANSPORTIN-3; 1.
DR Pfam; PF05347; Complex1_LYR; 1.
DR Pfam; PF06391; MAT1; 1.
DR Pfam; PF08389; Xpo1; 1.
DR Pfam; PF17121; zf-C3HC4_5; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 1177..1196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..137
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT COILED 184..211
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 265..306
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1211 AA; 137568 MW; F9B0CFB85B175FD9 CRC64;
MTSPVARSVW VNLYKQLERE AAKFPQYSYR EFFKRRIRDH FEANRQVTDP VRQAELLKEG
KEGLEALRRQ VTISSLYPHK KTVVEQDVAK MRECGKCKSN EYTNKNLVMM VNECGHPLCK
NCVDNLFSRN AGPCHVCGKT LRRNNFWEQI YNLKKDDFDT LREYNDYLER FECIVYNLAS
GIDVEETEAE IAAFKERYAE LIERNKKKLD EDQLWIMQNL KEDRDMKNRV DQAHNQENQE
VERSAVKDTK AIMEELRESN VPAEVILDRE RKRQIEQELE EKEEAARRKK RNKELLQDRK
RMAESMSFST SQRMSGRSFE YKPPRLLING PPLPSKEELE AKGYLQHIRA ASMHGLAACR
HLVRTVQVQA WTLCDRILCE RRDPLACCFA AQTLRQKIMK SLSELPKDAY LSLRESLISH
LSHIDVSCHD QVADATATQL CLAVADLYIQ VPEWKNWVAE LLNRFTALEG DRTRMLLTLL
RVFSEEVQFS KVGENRRNEV RSELAASGES VAAYLSQVLE AYSNDHDMIK KAAPNAPNFL
HDAATECAVS ALIRAEDHQT HQALAMSLQA GVYQLHAAFN AAVSMEDMDK LQNFARIFVE
LAETLLEKIV NEGSTDPKSM GSIYTLELLL LLAGHHDYSL IEMTFNIWYR ISEGLFSFED
DQHIEKFKPY VQRYLAALYR HCRYDSEEEG VPDRDGDFMD FRLKVVETVR DVVFVVGTEA
CVRSMHSMLM SCSQSGTWDE TEAALFIIST VINNIVPLSF FSEENSVVPE LVTAIIGLPP
SSHPALLLTS IDLIGNASEW LSKNAVFLGK VVEWLLHLAI TPLFAAPAAE AIDKIVARSS
SELIHLLPLL MQLIPHLESS QSHGKKMESA IGSCLKASTL LIMNLPEEGI RQRITELCQP
IIQRLQMVLS STPVIAANNE NEKAADSWAR FAGEPVLWID RIATIFREVR PWNGGALKTV
NSNPSEQAPW LDIATELYGV LSESLKRYEN VARVVEHCCR SIRFIVRSLG IQSIGFVEPL
ITQMMDLFSR QQHSCLLYLA SILVDEYGGM ESLQPGLMIM LETLAHGTFT VLTLENGPRD
HPDTVDDLFR LAMRFVTRAP SSFFVHPVAT ALFECAMVCL SLDHQEANRS VTRFFTSIIE
QLLSARKTGF RDPSVEAAEE LVVLHGAKLI ELCLHAAIFK VSSNGAGLIL LSVFIINKRG
SEKKHRQPAV S
//
