ID A0A0N4Y0I1_NIPBR Unreviewed; 185 AA.
AC A0A0N4Y0I1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Presenilin spe-4 (inferred by orthology to a C. elegans protein) {ECO:0000313|WBParaSite:NBR_0000903501-mRNA-1};
GN ORFNames=NBR_LOCUS9036 {ECO:0000313|EMBL:VDL72625.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0000903501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0000903501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL72625.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01020082; VDL72625.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4Y0I1; -.
DR STRING; 27835.A0A0N4Y0I1; -.
DR WBParaSite; NBR_0000903501-mRNA-1; NBR_0000903501-mRNA-1; NBR_0000903501.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IEA:InterPro.
DR GO; GO:0016485; P:protein processing; IEA:InterPro.
DR InterPro; IPR001108; Peptidase_A22A.
DR Pfam; PF01080; Presenilin; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 152..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 185 AA; 20629 MW; 59C3C4B6A18CCB2B CRC64;
MRQTCQCDRF LCRLVSQFGE VSKLLRPVTL NMAMTLTAWI YVYDMKTDER LSAMFLMSGN
STTGNQYHDG IINAFSAMVV LAIVSFSMLL LALWDCRRLV QLDLLKSLKI SEEKIIYEYL
PGLVTAYGGF GCIVLRFLMF TADTKPVDAA SKKALQDAQD ADDAEADEDD SSSSDEDDGK
NVDNS
//
