ID A0A0N4Y7N1_NIPBR Unreviewed; 567 AA.
AC A0A0N4Y7N1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Intermediate filament protein ifa-1 (inferred by orthology to a C. elegans protein) {ECO:0000313|WBParaSite:NBR_0001217301-mRNA-1};
GN ORFNames=NBR_LOCUS12174 {ECO:0000313|EMBL:VDL75763.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001217301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001217301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL75763.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|PIRNR:PIRNR005546, ECO:0000256|RuleBase:RU000685}.
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DR EMBL; UYSL01020689; VDL75763.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4Y7N1; -.
DR STRING; 27835.A0A0N4Y7N1; -.
DR WBParaSite; NBR_0001217301-mRNA-1; NBR_0001217301-mRNA-1; NBR_0001217301.
DR OMA; HIQRQST; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 2.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR016451; Intermed_filament_ifa/ifb.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721:SF12; INTERMEDIATE FILAMENT PROTEIN IFA-1; 1.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR PIRSF; PIRSF005546; Intermed_filamnt_Ifb-2; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PIRNR:PIRNR005546};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|PIRNR:PIRNR005546};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162}.
FT DOMAIN 61..414
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 447..564
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 319..413
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 567 AA; 65589 MW; 6F6EAFF0F32CB891 CRC64;
MSYSTTQPGG RAPLGGRQAG NVVSQDRMLK IVTEMRSGAG SGLSPFGQNA ASTIRDSRER
EKKEMSDLND RLASYIEKVR FLEAQNRKLA TDLDALRSKW GKDTHNIRNM YEGELADAQK
LIDETNKQRK DLEQQIKKMQ DELADIRRKY EDAVRGRETD RAKIDDLLVH LSNLESEIAL
LKRRIAQLED EVKRVKQENQ RLLSELQRAR TDLDQETLNR IDYQNQVQTL LEEIDFLRRV
HDNEIKELQT LASRDTTPEN REFFKNELSS AIRDIREEYD QITNVHRTDM ESWYRLKVQE
IQTQSARQSM EHGYAKEEVK RLRTQLSDLR GKLADLESRN SLLEKQIQEL NYQLEDDQRS
YESALNERDS QIRKMREECQ ALMVELQMLL DTKQTLDAEI AIYRKMLEGE ENRAGLKQLV
EQVVKTHAIS QETDTETMRV VKGETASRQS FQRSAKGNVS IHEASPDGKF IVLQNTHRAK
DESIGEWKLK RRIDGKREIV YTLPKDFILR AGKSVKIFAR NQGVASPPDQ LVYDGEDSFG
SGNSVQTILF NKEGEERATH IQRQSTA
//
