ID A0A0N4YF82_NIPBR Unreviewed; 3399 AA.
AC A0A0N4YF82;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 2.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Titin {ECO:0000313|WBParaSite:NBR_0001540201-mRNA-1};
GN ORFNames=NBR_LOCUS15403 {ECO:0000313|EMBL:VDL78997.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001540201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001540201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (APR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL78997.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01021723; VDL78997.1; -; Genomic_DNA.
DR STRING; 27835.A0A0N4YF82; -.
DR WBParaSite; NBR_0001540201-mRNA-1; NBR_0001540201-mRNA-1; NBR_0001540201.
DR OMA; CHATNTH; -.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR CDD; cd00096; Ig; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 11.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45080; CONTACTIN 5; 1.
DR PANTHER; PTHR45080:SF8; WRAPPER_REGA-1_KLINGON HOMOLOG; 1.
DR Pfam; PF07679; I-set; 9.
DR SMART; SM00409; IG; 10.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 11.
DR PROSITE; PS50835; IG_LIKE; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000271162}.
FT DOMAIN 360..447
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 847..935
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 963..1054
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1182..1270
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3102..3167
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3171..3269
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3279..3383
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 111..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1370..1417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2024..2054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2185..2206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2238..2264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2388..2494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2556..2688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2811..2832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2976..2995
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3057..3082
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2433..2463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2582..2598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2599..2622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2632..2681
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2976..2994
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3399 AA; 379193 MW; 6A8E2E164EB11298 CRC64;
MSSGYMEIHR GIEFSAFPLR NAVAAVTRSA KPSKQMRPPV SPGEHLSRNI MSTSHHSGAL
APDGQELVQT HQFPQLQMVN VYEVNYSQRS SSVPRGVRHL ESHVEIPISP KRKISLEQHR
AEPSATPKTL SDRLPRSLYK TRSEGGARYL PHAPKFITSL PSEIMVNPNE KLVITVDVTA
IPTADFKWDV NGFEVKPSKN ITVLNEQNRS TLVVQPPVKQ GKYHVVAFNE EGRESLLTRV
VHEVTSTFEQ VQTEISIDTK PRPELLLESS VTVTSPRIAA DSEMVNSMES TVSTTSFKTV
HRREPPTREE VPPTKTLKTD DGIAREKLIK RPIDDETTMT TSYVKSTSTT KTLENIPKRP
TLVSAPIQSI HLKAGEVLVL ESRVDSSPPA TFRWYVNNFE AKNGQFVSIT QPCDNVSVAT
FSKPSAGHYK VVAENPMGDV TSVTRVTTEI VTEEFEERTT VTTSVKPSIF TLTKKPTIMV
REDLPKAPRI IEKLPTHLKV GQNEPVTLKV TADAIPEATF MWRHNNFEVK KNQNITINKV
ESNICELHMQ KAQPGRYEVI ARNHMGQDSC SCKIIVHYDQ EVPPPPPKPT FTKSLLEETT
IHLDERSNIE VIISGTPPFS FKWLVNGQEL SPGKDCEIIV EGNRSSLVLL KPIGSGSVVT
VEVRDRYGFT QSETKVKEVS KIVEVSRVEE RQEESKPLGD APVFVQKLEN IEIVEGETLR
ARVKVTEESG ACTFQWFANE MQITSGDQVM IECSPVESRL TIEDMGEMAN VQLAAVAHNQ
YGSSASSAIL TVTRRPDESF EMVPPDVPEE SAPKIIEPLH SASFIDGKEN FEISKKTLYY
RVPSSGPQSE FLDIFKSQPM LLRCRIEAVP SAVIVWSKDD INVDEWVINK DVITQILPGG
ICELMNPEVY PEDSGLYKCT ASNPHGTAET AAYINIEGPD YRKVEEGSTS ESAGQPEELI
WPPKFAEPLT AETDGAYDLN YVRLICRVKS AAPTTISWLR NGVELLPSEK YEFHEFSDGA
LILTIYSPCD EDNGIYTCKA ESAHGLSSTS CQVVVPTRTT TTDTEKLCES TITTISNEPA
STTTPSDKME DQSGAEVTET TITTINLEQA PEFVADTDKE DTVAVTEITK HEEQYKLLVK
VADSVASALV ANVFVDAVRE AVKRIMEEES EEEEEVEPAN APRFETSIER YVVRENDTVT
ISTKVSGDPL PFIEWYFKEE KLSLTEHISM GYENRVATLI LKNVTLGQEG TYYCHATNTH
GTTVLASEVK VLPEKANDKV RFSLARYDKR EFSEYVVMNV FAYHEDEHDM KSIELKDTEK
EDISTHCTAA PAAKPVQEII SEKRQETVEI TPTAAPPESA EQVLPNVQKS VETTSSTQAT
PAEEEPIPAQ PAEEEQAPVP KPRKRATKET TAIVETTSLE IEEEDVRKQR EEKEAQERSA
RLIAVKFAES FTEKVMSQEI VNEEDATVDV RKPDVLFEHV VTVVEPEVVQ LGLHLPAVSV
PSMKFIDLET ILQRPGTSSS ANTLITSPNR GSANAEHRIV VRKLATESAE PTAFVQVEII
KPSEAKEEKL TIVNHEKIIP DLMRVAAAAS KMKLENVTVS LVRQGATSHQ ELVIEYESCV
EDSAEFNLSQ LVYSPPKEDS SSQEVWSRRS RYSKVDENVV AVFMEVDANC PDQCVEVVAS
VSIPLQEKVE GQRSPSPELM EVSESITESS SAIGQQVPRF FRTLNNCEAV IGRSAQFKCI
HRFIEHAPSM TELIESDVAA DDPENSFDSF EFEESKANRL FPSDTPSLQR SVTYNSEFDL
SRIVNYNEDM VETNAFHKYF DTAEATVKVA EWERRERVFA TFIERLSETA YVNIIIPKPA
AASSAVHIIA ERGFLGTHSK IFGSCTEIRR TKTEQAEKDS ENVEKKLDEV VSTPREVDLP
EKLSYKGREI GVSVSEIEKE ETLVNKDGDV EIVKKKCMET SLEFDAELDI KQSIRKISNA
LPRDEPTSLP ETPKTKPDIE QLYKEIFEPV VKEYEIGDIS KSVSESHRFH SSPTAAPRPL
ARAKKSASEG ADKMQSSVFD PDFISKMKEI ERIARQVDEE LGQLSSPVPP QDENVKEIEE
AIFKISDQLV LAHPITEAQA EASEELLRTT LADMILNPAR TAEEELELMK RPIRLLRRKL
SDLENSLMED AEVTEIIDHP CETTEVNGVG SESGPSLRIQ HGPKTRRVPS AEYLRVTPLT
SNIKDQLSCL EQMITEHMNS ESPDSATEGN EEATSRSKKV ESPKKRELHD LFVQINAEIN
TIKTYCKSRI SKRGTDAVMN VLQKVRTHVT SIVNVMSLSK KKQLKSKLEP TINYEFTRLP
ANEKMEVLLI VNLPPPDDSV NRKSSTTLST SDDTWRYSTE LKSLEKPELP KEVPIAETIE
QETTVRVTEV EAPQPPPRRR RTTSAEPDLN TEPPTRPPRR KRSDIKARDS SLDSKRTHLE
TEKKYATIGP STVPFKDKDP VPPGSPGKAK RSFAGDTLDL IRNLSCMRVQ KGQQDDLEKS
LLEELSQMTV SRHEEDDVLS EPEWVQSEVN ESLKIGMERA KLGEGSNKLD VSSYSNEKSA
SAPEEGKPKP KSSGESDLES GSRNDGGSAG EPNPQVTAEP GTSSEYIDGE IVVQEEESHE
KPKEIQKEKE RLQEEESKPE DAYEDETEKQ KKEEDKQPSP QSEECAHSSF EATSLSAAYL
MLAEASATLD VPITNWATLT ENMFTEDGIC SVQLTCEESD YGTDTDTSAY LRGTVQFFNR
NSPRDATPQS LSSMGMSQRS SKILPDVSEE QDELPTIEVV ADVDLQKCEK PVEDEENAEK
ADAGDAASVR LSVTSSYSPE KASEISDETV HIVLEETLLS QMASSEVTDD TDRMTPLSRI
GVRETDILSD DSIVTEIDQF IVDEVLESFS FVRADAKKGV IAIVFLELRQ CVTARIAENT
FDVEIYQEPE NLALVIRVVE DQVNSTSLTI AEYERTDTDQ ESHENFDDTS SFDDVGGEPR
TGITVSIIAR SLHDGIYASL EEIPWGEVEM TLPECENMTK SVEEDSKMSL QFNVTVSESN
PDERKSLRSQ ASLNQSQNTI SEADNTLSTG SINIPSYVIK LGSTATITCE LNNYLPANSR
IDWYKGMSQI DTYPGKVDRI SHDLLEVLII HNVQMDDNEL YSLKVNDDIF PVAYLIVEQA
SSDDNLAVIL SPPQTQFVME GQPTVLMCQV SNPSQEVVWL KDRKPLQESA RLQLETGDDG
WNRVVFSQTR MSDQGTYFAC LGQQSVAITL VVEERIDEKE VTVVASGTES EDDDVQEYLM
PPGSTATIAC ELEDGDRVHN VVWLKNGQEI KFTDPNKMEH VVNGLKHYLV IHDSSYKDNG
LYSVSISNVE FRVAHLTVND VVTASQNLRR KRISNSSLH
//
