ID A0A0N4YPL2_NIPBR Unreviewed; 221 AA.
AC A0A0N4YPL2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Macrophage erythroblast attacher (inferred by orthology to a human protein) {ECO:0000313|WBParaSite:NBR_0001918301-mRNA-1};
GN ORFNames=NBR_LOCUS19184 {ECO:0000313|EMBL:VDL82913.1};
OS Nippostrongylus brasiliensis (Rat hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0001918301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:NBR_0001918301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL82913.1, ECO:0000313|Proteomes:UP000271162}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYSL01023956; VDL82913.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N4YPL2; -.
DR STRING; 27835.A0A0N4YPL2; -.
DR WBParaSite; NBR_0001918301-mRNA-1; NBR_0001918301-mRNA-1; NBR_0001918301.
DR Proteomes; UP000038043; Unplaced.
DR Proteomes; UP000271162; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd16659; RING-Ubox_Emp; 1.
DR InterPro; IPR013144; CRA_dom.
DR InterPro; IPR024964; CTLH/CRA.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR045098; Fyv10_fam.
DR InterPro; IPR044063; ZF_RING_GID.
DR PANTHER; PTHR12170:SF2; E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA; 1.
DR PANTHER; PTHR12170; MACROPHAGE ERYTHROBLAST ATTACHER-RELATED; 1.
DR Pfam; PF10607; CTLH; 2.
DR SMART; SM00757; CRA; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS51867; ZF_RING_GID; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000271162};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU01215}.
FT DOMAIN 27..71
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT DOMAIN 143..211
FT /note="RING-Gid-type"
FT /evidence="ECO:0000259|PROSITE:PS51867"
FT ZN_FING 143..211
FT /note="RING-Gid-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01215"
SQ SEQUENCE 221 AA; 24801 MW; 77C235A5E90FC716 CRC64;
MLRCGHIESA TALAKEMDVQ DIVDLEVFNK VEKVVDALLN KDTGPCLEWI VEHRSKLRRM
NSKLEQIVRV QLMGLIALCA NNSVPAYKEL LSEQRWQSLA DLFRQEVFTL YQLPRQSAFA
VCLQCGLSAY KTPHCSPGGV ERCPTCQPCA YALAEGLPYA HTVNSRLICS YSGEALNEEN
HPMMMPDGRV YGEKAIRELQ VRFERFASAF TIVNIGGIDC V
//
