ID   A0A0N4YXS7_NIPBR        Unreviewed;       423 AA.
AC   A0A0N4YXS7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Exosome component 10 (inferred by orthology to a human protein) {ECO:0000313|WBParaSite:NBR_0002204901-mRNA-1};
GN   ORFNames=NBR_LOCUS22051 {ECO:0000313|EMBL:VDL86604.1};
OS   Nippostrongylus brasiliensis (Rat hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Heligmosomidae; Nippostrongylus.
OX   NCBI_TaxID=27835 {ECO:0000313|Proteomes:UP000038043, ECO:0000313|WBParaSite:NBR_0002204901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:NBR_0002204901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL86604.1, ECO:0000313|Proteomes:UP000271162}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UYSL01027320; VDL86604.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N4YXS7; -.
DR   STRING; 27835.A0A0N4YXS7; -.
DR   WBParaSite; NBR_0002204901-mRNA-1; NBR_0002204901-mRNA-1; NBR_0002204901.
DR   OMA; FICATSH; -.
DR   Proteomes; UP000038043; Unplaced.
DR   Proteomes; UP000271162; Unassembled WGS sequence.
DR   GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR   CDD; cd06147; Rrp6p_like_exo; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR045092; Rrp6-like.
DR   InterPro; IPR049559; Rrp6p-like_exo.
DR   PANTHER; PTHR12124:SF47; EXOSOME COMPONENT 10; 1.
DR   PANTHER; PTHR12124; POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED; 1.
DR   Pfam; PF01612; DNA_pol_A_exo1; 1.
DR   SMART; SM00474; 35EXOc; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000271162}.
FT   DOMAIN          204..372
FT                   /note="3'-5' exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00474"
FT   REGION          151..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..170
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  49027 MW;  A7EE2458F8F2FE83 CRC64;
     MRNTGCPTRM PKLYCEAEEY IERIVMVDDH IVERAGILMD ELDRGGREDV EVPKAVIGAE
     STKRRKAEAE ANFQERIHSS DPGFVLAEQL RLAHEEAKAA KVANVSVKPQ KEYGFESSID
     NSTNPFVPKL RTKHHALPRK EVSGMIVIDE NDGQKRNVGS NSSQNDVDDS SHPYTYEIQN
     FVVPDSQMES RPPVKPLEFK DTPLKMVKTK EDLELLRDTL NKCKEFAVDL EHHDFRSYLG
     ITCLLQISTR TEDFIIDPFP LWNEMHILNE PFTDPAILKV FHGSEHDIEW LQRDFGIYVV
     NMFDTGRAMR LLDMQKFNLR FLVHHYCDVL LDKKFQLADW RERPLDEEMI NYARGDTHYL
     LYCYDRLREE LLEKGDQLKN LLRVLYSESA FICATSHGEC IFDNGLGLVQ TPRDETAKSK
     RNR
//