ID   A0A0N4Z0F8_PARTI        Unreviewed;       670 AA.
AC   A0A0N4Z0F8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Translation initiation factor eIF2B subunit epsilon {ECO:0000256|ARBA:ARBA00044144};
DE   AltName: Full=eIF2B GDP-GTP exchange factor subunit epsilon {ECO:0000256|ARBA:ARBA00044345};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000019000.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000019000.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
CC   -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC       {ECO:0000256|ARBA:ARBA00007878}.
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DR   AlphaFoldDB; A0A0N4Z0F8; -.
DR   STRING; 131310.A0A0N4Z0F8; -.
DR   WBParaSite; PTRK_0000019000.1; PTRK_0000019000.1; PTRK_0000019000.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR   CDD; cd11558; W2_eIF2B_epsilon; 1.
DR   Gene3D; 1.25.40.180; -; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR003307; W2_domain.
DR   InterPro; IPR044123; W2_eIF2B_epsilon.
DR   PANTHER; PTHR45887; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR   PANTHER; PTHR45887:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   Pfam; PF02020; W2; 1.
DR   SMART; SM00515; eIF5C; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR   PROSITE; PS51363; W2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          506..670
FT                   /note="W2"
FT                   /evidence="ECO:0000259|PROSITE:PS51363"
SQ   SEQUENCE   670 AA;  76742 MW;  8606E044A4001018 CRC64;
     MVPNLLSKEA LESLDSTLLN EEPLKKFGCV IVADNFDKSF TPPLIDDPWV GQKLCGLPLI
     DFLLVSLAKT PVTNVVVMSS NFPPKWIEYF SKKYYNHFWE IKFVEQKTAN SVGDILREVR
     QRNLLNIDFM LIPNILTLIA GDFKREIYEF IEGRVKNHDH LVTCLYVHSH DPQNLFVINS
     ENGKVVNFNS DFNSKKSKIT KRAFIENLQY CSNLKPLPLW ICGKEVLDAF SENFDLTDIE
     DLMRHILANE EVMCAYTCMR KVSENSYASE ANNFVEWIAL QSKFLRSCFY PLKPIQVAVD
     NNHNVNLLQL YHSVYIGHNR NDLNFRSKGV TTKNSRRSYI GWVPNNSADL QLEMIDSSIV
     GAINLVRKSS FKQCMIGKKF KSDSLLSLQK CIIGDNVVIG KNCKIGKEVF IGNDVVIKDN
     ETIMDNAMIF SKPVDNDDNR FTSTLHGNYY IWKSVNNVHL WEGNSLSSSF KCVLKDIFCG
     VEDNNDSDDE INGTDHIADS SIKTEQNCLE TFASEVKDSM LATLQSTNPF DQGNVRSLIL
     EINSSKMVHN VSMDSVCLTV ITTLLQIEDK ITWSRIEELL NGWMTIILNY FSNDHSKKLI
     LVAIEDIVKH NEALSKILVK VIHMFYNEDI LTEDFIIDWY EKLPEDNKLQ ADAKVLYDWL
     CEESDEDSDE
//