ID   A0A0N4Z2Q3_PARTI        Unreviewed;      1195 AA.
AC   A0A0N4Z2Q3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=3'-5' exonuclease domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000114700.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000114700.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000114700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N4Z2Q3; -.
DR   STRING; 131310.A0A0N4Z2Q3; -.
DR   WBParaSite; PTRK_0000114700.1; PTRK_0000114700.1; PTRK_0000114700.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR   InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR47765; 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR47765:SF2; EXONUCLEASE MUT-7 HOMOLOG; 1.
DR   Pfam; PF01612; DNA_pol_A_exo1; 2.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 3.
PE   4: Predicted;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022839}.
FT   DOMAIN          322..417
FT                   /note="3'-5' exonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF01612"
FT   DOMAIN          1101..1162
FT                   /note="3'-5' exonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF01612"
FT   REGION          1037..1091
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1037..1052
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1054..1078
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1195 AA;  140117 MW;  9A03064E31F3F2A0 CRC64;
     MSLSIPTLRK VILISFYWYY FLTCPDGKDE LIMKRKDIKD ENVDMKKKIN FNITIKDHTS
     ILEMICLTGQ KDRNSLVLMH IHNFGLLRSR EQFCQELICM ANSGRAYFQL LNFVLTDKRN
     IQYIDSPDLY IKLAFLGPIH LSSLENVVRD KDERFFNKII EVLKILKCCE ESHELYVELY
     QKHLKKVPEK DNYLNFQKNI KTLFKQLRME DTDKKVMSTE TAIVQLKRYS RMRYKEKKID
     NHHLNDVAYT IICQYPHFKN TFINILIKEK DYDEVERWQC LEIEDNQFPK YYPFEDKEND
     CIYLENNDYL SLPKHITVKQ CSTNEEILDV IESMKKANKE GFTIVGFDCE WSSFNGSENV
     SLIQVSFNDI CYLVDACYGD KEMISEFLST LFECENLIKL GKSPKGDIDV LLKTFGTIKS
     LYNPTYTLCL TDVVQIFNAA NTDKHNNDKN FIGNFELYVP KWKEYFNQCN IPKQEDEGKE
     ELKEEEIIDM VDEDEIYSDV IPTSESLPGE EKEIEEKVNI RKQKIKKPKK SEKEIFTQLI
     DSAGLSKLCQ MILNKELEKV EQCSVWDRRP LRLSQIMYHY TQLAKVTLKE SNKKRHPGKR
     NDKKSKEEGM TDINGFIVPY KEHIKIMNKI FHQSGDKGMF LVKFYVETFK HLMATVTKFL
     AELIKYTENG DIHHDMFSFI FSNRNFKVFI NDVKLIEKYF LVSSINISAI EKIVQGNKLI
     NHDDVIEMFS RLKRCTVDQR YWNHLFEELF KIAPTNDHYS KFLINFKTFT EEMSQDTFKK
     TPLPYGKCCG VLFYTLKKRY IEQSIDDYAL NDVAYAVISQ HSGLRKKLLI ELKKYKDFKA
     LKLWNKLYVC QNNFPNYFPL PENKNESLYV NKDYLELPRK INVVFCVTGN DISDAIKAIN
     NANKKGFQVV GFDCEWSSIQ VPQYVSIIQI SLNNTCYLID ATFGCKNSIQ KLLETLFNCD
     NLMITGLQPV NDLKALILEY NNVEALYTPK HVFCLTALII AINDAKSIKS EEIDNDPNIA
     GNFDFIFPNW RESIKNTKND KNEKKEDESF ESYESQDNCS VKSSDNHDNC SVKSMGNQSD
     KNDETKKSSS KKEVEVLTEK KKFEQFIRNK GLSKLSKLFF DKEMDKSEQS SVWDRRPLRI
     SQIRYAALDA EVSCMIFQKL EEICNMLEIN IQKIARELPS NQVCKPLLLT LFKQS
//