ID A0A0N4Z3Y1_PARTI Unreviewed; 577 AA.
AC A0A0N4Z3Y1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncoordinated protein 58 {ECO:0000313|WBParaSite:PTRK_0000169300.1};
OS Parastrongyloides trichosuri (Possum-specific nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Parastrongyloides.
OX NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000169300.1};
RN [1] {ECO:0000313|WBParaSite:PTRK_0000169300.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR AlphaFoldDB; A0A0N4Z3Y1; -.
DR STRING; 131310.A0A0N4Z3Y1; -.
DR WBParaSite; PTRK_0000169300.1; PTRK_0000169300.1; PTRK_0000169300.
DR Proteomes; UP000038045; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR PANTHER; PTHR11003:SF310; UNCOORDINATED PROTEIN 58; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 249..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 354..412
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 470..537
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 577 AA; 65165 MW; 1BE706BB4BFDF4CA CRC64;
MFFYSPHPKT TIVRRPTIFP SQLREITAIA RENIDHINRS PLIHHPSERA SITRRWNVDD
PAVNIVDETT STHTRRDRGV ESAPLIAASV AVLPFALDAS TNQRAYSQDF QAESGGLNNN
VPINNNVTVR RHGTISHPTS YLQIVHNAGD NVALSPSESI VSREHEHNRR LSKVGKSIYL
RRPTISIQED GRIVIDHVGS RWDGIPLTSQ AGLIDDDGAT IITDTLKDDG EGKEPLTCPQ
QTVKYIKILI PHVILVSVLV GYLCFGAWIL MLLETRTELM ARSKKLVRLT NLMTNFTSHS
WLTLNDVQNG IRSIDHDEWA SQFREYMVSV SELVDDRRPI RKELIQPDNL DNMHNKWTFP
TALLYVLTVL TTCGYGEVSV DTDVGKVFAV VFALVGIPLM FITAADIGKF LSETLLKFVN
NWNRMTRQCK RYIRRKSLQE ANGNLETLEM LGIDGAEEKL WFPIGAYVGC ICLYCSMGSA
MFINWERTWS FIHAFHFGFN LIVTVGLGDI VVKDYLFLSL IVAFVIVGLS VVTMCVDLAS
THLKAYFTRI HYFGRAKRFL GMSEELREIV RFGINSP
//
