ID   A0A0N4Z9Q4_PARTI        Unreviewed;      1337 AA.
AC   A0A0N4Z9Q4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Histone-lysine N-methyltransferase {ECO:0000313|WBParaSite:PTRK_0000411600.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000411600.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000411600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   STRING; 131310.A0A0N4Z9Q4; -.
DR   WBParaSite; PTRK_0000411600.1; PTRK_0000411600.1; PTRK_0000411600.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR006560; AWS_dom.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR22884:SF413; HISTONE-LYSINE N-METHYLTRANSFERASE CG1716-RELATED; 1.
DR   PANTHER; PTHR22884; SET DOMAIN PROTEINS; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00508; PostSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS51215; AWS; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          500..553
FT                   /note="AWS"
FT                   /evidence="ECO:0000259|PROSITE:PS51215"
FT   DOMAIN          555..672
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   DOMAIN          679..695
FT                   /note="Post-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50868"
FT   REGION          336..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          702..745
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1010..1040
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1113..1245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..393
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        453..472
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1337 AA;  154242 MW;  5D06E48A8422E64F CRC64;
     MNEETNDANI SIVSLPPPRI RKVRSPKNLI KLTAILPRST SQEGKLKKFK TVKRNLQSQN
     QGCGQTKIPV IKFVMNKNQE VVNNDTTITN NAPVKLYEIS QPVVRNSIST SGKTMIIKNK
     HNLQPLNDNK NLLGGANILL QNRLPITNNG VTTTNKIITH VDKVVTNSGG QKIIKCLSPA
     INKIVSQQAK SIPIPRVIST PRSSVIIGSD NKLFSCTVGM GKRQNVCINN MQNEISPKNN
     FPIASVSANE DNDSNVEDIK IVEVEKKNDD IIEEGTKIIQ ETTQDKDKHI HSEKEIIQEE
     KKDNIEESKD SHNSFINSID ADFEYALKLQ RELDAEEKRS RLRKKPEVKN EITPKFPSKD
     TITKKKETVS KKKELKSKEE NNDSDTEKLS QMSGKKKRGR KSRVERLNNT KEDSSTPSVE
     EQNDGNSGPK KRGRKPKNGA STTPSIDLEE SSISPVDKVE EQKSDTKSEE VDTTSQPKTM
     GFIKIVKNVY RCTPDTDYRL ADEVCDCKPE DPNNIEKNSG CGENCISRCM NLECHGCAFG
     RVGCSNRRMQ RRQNAPVEAF WAGVKGWGLR AKADIAKGDF IMEYCGEVLN SKQEARRARR
     YAKIKQNHHY FMHLSASTTI DAYYKGNISR CMNHSCNPNA QTEKWRVKGV PRVGFFAMKN
     IKKGEEICFN YHFFNYGKEP QKCYCGSKNC KGTIGEFVPM EERDVDSDDD YTSSSNTDTD
     SGESEGEEEI IENINNEEKG DKKECIKEEG SASIIIASPP KNKSPVKVAV DNVEEEPKDE
     DGSEEDEDDY DIPLKPIIVM KEEPKIEVVK LTEAQEEKVK SFSEKVKTLH NTVTEELKSD
     KLSSCSVDKC CDMLKECFSI QQSKLIIPIV LMITEKKSRE IQLLKNNILK ILADHLTFKT
     FIDGLSYPIH TKEMLNYIDQ LVESITNIML FNDISKYAKY IAESQLEIVF LEVFTILTQI
     CKSNDGEISK ISSNIRDKIA YTKQKAKMYV EEDPDAMKCT AIIEDKYNRK QRQEDRHHYH
     GRSYKYNEYR RHRSENRERR NCEGRGRYEI NNRRGCFENS RNLHKRKRDS SRDGYYYDSK
     RYRSDFRGDS YRGSDFKRGY ERSYKNKWNY HNSRSHERKY PNEVRKRSRS HSNERFYYKK
     SKRYSRSPVY DRKDKDYVRR SDIHEKRSIS PRNDSYRRDS YIRKRDSRSP RRNLSRCISK
     ERLRDRRDDY IKSSHRDSNK KSNIVKSDKY YDKKRSNSPS SKLHRSNIED IKKKCDETKA
     AHNTHSKEES LKERLHKLIP QETIKAIVDS IKEPESEVKP EIVKDKEISD VFFHKQINSA
     SSKIKALHGS KPIFEKR
//