ID   A0A0N4ZAV1_PARTI        Unreviewed;       671 AA.
AC   A0A0N4ZAV1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Tyrosinase_Cu-bd domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000466500.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000466500.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000466500.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR   AlphaFoldDB; A0A0N4ZAV1; -.
DR   STRING; 131310.A0A0N4ZAV1; -.
DR   WBParaSite; PTRK_0000466500.1; PTRK_0000466500.1; PTRK_0000466500.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00497; TYROSINASE_1; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          65..82
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00497"
FT   DOMAIN          212..223
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   671 AA;  78189 MW;  FE22ECEA81AC7FA4 CRC64;
     MRKRREIYDT IKRRLIRKEY RMLTNQERES LHNAMNELKQ KTIDNITLWD LHILIHYPDS
     APGAHWGAAF LPWHREFLRQ FENALQNINP NVALPYWDST LDYGLPNPSD SIIWSEGFFG
     NGNGYVKTGP FKDWTTNVLM PLSDVKIKKL YRYTGGKGDD RLLSPDDIDW ILNRNHYANL
     TFCHDRTFES MHGLSHVWVG GFMFVIRVSP NDPAFYLHHA FIDSIWERFR QSKQTRLQRE
     TEYAENTCGD LHSPTAPMKP FSLTNIDGLS NDYTDYYYIY QNVKHCSILD PVCHDSPYYW
     CDRRVWKCKS KIQLGGNCTN LEGQDACYAS TCIQGICQYS SIEGNGMQRR QFIPTNVVWA
     KSLLLNNDNK PITHPLAHIN VIDEYQNFNV TTFVEMQQNN FEYNGMIYLA LPKPSSGLST
     PITLLAQDQF GRYCQSYCIN ETTQIYDVCE PKMILKIRKD YETANIAYTH SYMSRNYLDL
     DFSQHPSKIY VNPPYMIFSC NSKAVDKQEI FNSVKNMIQF SKPLEDFVWF RVELLQKYES
     PYNIDNLVVK IIDMDDSYYN WQESVPKIKS PVDPNIIFVK APNPYVNGRG IVVRVLVLFE
     GQMINCIAKC SKSNERIKSN CSEEVILHYI PILGDENLFT ANESILSLIG WKMIGHPSKW
     DYKLPYLSLT C
//