ID   A0A0N4ZC99_PARTI        Unreviewed;       697 AA.
AC   A0A0N4ZC99;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   22-FEB-2023, entry version 20.
DE   SubName: Full=ShKT domain-containing protein {ECO:0000313|WBParaSite:PTRK_0000515300.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000515300.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000515300.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01005}.
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DR   AlphaFoldDB; A0A0N4ZC99; -.
DR   STRING; 131310.A0A0N4ZC99; -.
DR   WBParaSite; PTRK_0000515300.1; PTRK_0000515300.1; PTRK_0000515300.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   CDD; cd09823; peroxinectin_like; 1.
DR   Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR   InterPro; IPR003582; ShKT_dom.
DR   PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR   PANTHER; PTHR11475:SF61; PEROXIDASE MLT-7; 1.
DR   Pfam; PF03098; An_peroxidase; 1.
DR   Pfam; PF01549; ShK; 1.
DR   PRINTS; PR00457; ANPEROXIDASE.
DR   SMART; SM00254; ShKT; 1.
DR   SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR   PROSITE; PS50292; PEROXIDASE_3; 1.
DR   PROSITE; PS51670; SHKT; 1.
PE   4: Predicted;
KW   Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..697
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005891477"
FT   DOMAIN          32..71
FT                   /note="ShKT"
FT                   /evidence="ECO:0000259|PROSITE:PS51670"
FT   BINDING         467
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ   SEQUENCE   697 AA;  76975 MW;  08C80A7F4D44D455 CRC64;
     MRHISTIILI IFFCIEKISS ELSPPITEKF KCLRNGCCDQ HEWCRFWASI GECRTNSEWM
     NISCQLACNT CKSSSRGTEP ISHQSSDSSL SKDLGSCEGI RKNPSTAIED LKKSGLITPV
     EDISSRIILS IDDITRSVPT GCVPQIASAD CRKALCYHLS YRTFDGTCNN LDNPLKGAAF
     RQYLRLLPPA YDGGSMGEPV DSLNPTRPTA REACRLLLSS GQVVNHDTFN TLMMQFGQFL
     SHDMSKTTLQ PTSQCKNCSP VPSKCIPIKI SPKDRNEGFK KKECLKMSRS APICGTGQTT
     PRQQLNENSG FIDGSAIYGS STKDLHKFRE GRTGFLKMTA FNNKLFLPFD TSKCVSKQNC
     VASFTTGDIR GNLFVGLASL HILFAREHNR IARSLQAMNP GWSGDRVFQE ARKINGGVLQ
     HIVYTQYLPK IMGTAMDSII GSYKGYDNTV DPTVSNVFVT AGFRFGHGMI QEVFKRIDGS
     GNSIPDGPLN FGDGVFKSAK LLFEGGIDPI VRGLLLQPVK RPHRMTPAIT ERMFGSTDLG
     AVNINRGREH GTPSYNAWRE FCGGKRATSF EDFSDHILDK NVRGGLAKAY QSPDDVDLYV
     GAMLEDPVVG GLIGSTLSCI VGNQFKRSRD GDRFYYENPG IFTPEQLQQI KNGSLSRIIC
     DNGDSFQVIT EDAFLVPKNG MTACKNLPIV DLSKWKE
//