ID   A0A0N4ZKG6_PARTI        Unreviewed;      3255 AA.
AC   A0A0N4ZKG6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Vacuolar protein sorting-associated protein 13 {ECO:0000313|WBParaSite:PTRK_0000860000.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0000860000.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0000860000.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the VPS13 family.
CC       {ECO:0000256|ARBA:ARBA00006545}.
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DR   STRING; 131310.A0A0N4ZKG6; -.
DR   WBParaSite; PTRK_0000860000.1; PTRK_0000860000.1; PTRK_0000860000.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR026847; VPS13.
DR   InterPro; IPR026854; VPS13-like_N.
DR   InterPro; IPR049424; VPS13_C.
DR   InterPro; IPR031645; VPS13_DH-like.
DR   InterPro; IPR031646; VPS13_extend_chorein.
DR   InterPro; IPR031642; VPS13_mid_RBG.
DR   InterPro; IPR009543; VPS13_VAB.
DR   PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR   PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR   Pfam; PF12624; Chorein_N; 1.
DR   Pfam; PF21679; VPS13_C; 1.
DR   Pfam; PF16909; VPS13_DH-like; 1.
DR   Pfam; PF16908; VPS13_ext_chorein; 1.
DR   Pfam; PF16910; VPS13_mid_rpt; 2.
DR   Pfam; PF06650; VPS13_VAB; 1.
PE   3: Inferred from homology;
KW   Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          3..116
FT                   /note="Chorein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12624"
FT   DOMAIN          136..371
FT                   /note="Vacuolar protein sorting-associated protein 13
FT                   extended chorein"
FT                   /evidence="ECO:0000259|Pfam:PF16908"
FT   DOMAIN          559..782
FT                   /note="VPS13 middle RBG modules"
FT                   /evidence="ECO:0000259|Pfam:PF16910"
FT   DOMAIN          1144..1337
FT                   /note="VPS13 middle RBG modules"
FT                   /evidence="ECO:0000259|Pfam:PF16910"
FT   DOMAIN          2037..2528
FT                   /note="Vacuolar protein sorting-associated protein 13 VPS13
FT                   adaptor binding"
FT                   /evidence="ECO:0000259|Pfam:PF06650"
FT   DOMAIN          2841..3023
FT                   /note="Vacuolar protein sorting-associated protein 13 DH-
FT                   like"
FT                   /evidence="ECO:0000259|Pfam:PF16909"
FT   DOMAIN          3118..3226
FT                   /note="Intermembrane lipid transfer protein VPS13 C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21679"
FT   REGION          1568..1593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3255 AA;  369351 MW;  A1935F8CFFB35C3E CRC64;
     MVFESIVADL LNRFLGDFVD NLDASQLNIG IWGGDVKLTN LDVKETALDD LDLPIKLKFG
     YLSSLVLKIP WKNLYTEPVI ADIEGLHLIV VPSKGIVYNA EKFEKNLMEV KKKALERLEE
     ARKEKRKPKD PAADTFSEKM VAQIIKNLQV KIRNIHVRYE DKYTNRHRPF AAGITLEALD
     FITTDENWKA TIHKDVVKIV HKLVSLNNLS VYWNSDTKLI SDLTSKDDIK REMHNGITTQ
     SHRLKDFKFI LEPINMEAKL AMNQKPETDG SNWTIPKIDL KAGMDQLALA IGKLQYQDIL
     LFLEGQERFN LSARYIKYRP NLLEYRGHYK EWWKFAYNCI LHENIRRRKE NWSWKRMKKH
     RELFKAYRLA WIHNQTENSL SNQERDIITK AEKDLDVFNL NIARQQAELE IDRRGLKRTE
     DKPQGWVGWA SSWWGDSSTA NSKSIEEGGN IAKQFEQAMT PEEKAKLFEA IDYQENTPPT
     NYPKYYVENV VNFKLNKLKV MIQDALELKF SDFNVSLKQR SSARAIHLKS SIKKVTMSGC
     GVPMMALTDE KMEWLTMEVE TNPLQGDFDQ SVFLQIAPII LKYHAPAINT AIDVFKPPES
     VKLNQLTAAA MASYEDVKAR SVTGLSHAVD QKTKLKLDIR LHPATIVISE TGVFDENKPT
     LVADLGMLTI QTTEETHGAY DNVKDEKLRN LMIKAYDKFH MKLSNVQIIL AENFSKCMEN
     KSGKLSKYHI LEPTGLDIKI HKSSIDDLQI AKMRMFGNLP DFKIRISDNR LLMLMGLVFS
     IPTPPPDLVT DSEKEMIEES LRPKLKDRAK IKAIMDVQDV ENLKDDKDDK TQEDEDARRQ
     KMLDLQQVQF DVNLKLNEVA FILLKDDQEI LNASISRFVC EVKIRSFDTK VQLKLGDMIV
     TQPQFKSLDG KRPILYLIDN QLDVDEYLIT MDYIQANPES PFFEKEYKST LQAITFDFKT
     LNMSLNQQAL VYLKTFGEQL QKRIENVQAA KDGGVKQEVQ PAKRKISTSS LQSLTKLTIT
     GSNTANKKGT KKLSTPKALK KVDETKIIQM SLNASFNSLA LLIGTEKDGL LTDAVIKSVR
     CNIEMTKLKM KVFAALKEIC MNDYHPKSIH RHLLQVDGDR EMFTMYFTQY NRTEKEKARM
     SIDDVDMDVK INFAQMRFIF LNAWVSRMLN WITPFQEEAQ TAANAAKAKA SEKATQAAQN
     VKQLMEVSPP KIKMDIELGA PTIIVPKISH SYEALFINFG KLKITNSFFN GVEEPKSIID
     NMEISLTDTS IFGGEVQKGN DGLPFKCEIL KPVTFTLSVK RNLCFSWYKE FPAIVVEAVL
     PELDVSVSQG DYVNMMHTLS GNLAEGDIVA VEEKVPVIEQ DKITQLQLTK SPKPTDVKES
     KLPTIIEETP KVVKNSMPKI IFSFKIGLIR AGLYRGNSLP DNLTIQSPKN SSFTIPRDPL
     KAFAAMAVTG TKLSGMISED DSMAAEISVK AFTMNDERKD ATKIKRLLDK KANKSSEAKD
     FAHIIYKKDA LNNMIADVST SSFFICLSPE FLAILSSFFI VPPYKEGEEL RKIKEQQEVC
     AAKVQNLPNQ ENPNTTKKLD TSTAPKPPNT GTMTVRCNIR EMEVILIEKP MDPENSQAMI
     LSFNCSLNAD HKDDTQYVSG GIHDLQIFST YYAEEKKHLC HYPVLQPLNI SLDGSINDKS
     RDTELQISVG NVILRISPSI IRLLSAVSQE YSKNQVAQTT DKKKAAGLTA YPNYWKPSIF
     DKSSYRWFVS SAMECSEYFD EEVIKAKALI RPVERMKFML PSLLVTMESG TEKSTQPLIK
     FETTMKALVF DWSSLLSVDS SLTFQMSYYN ESLSIWEPII EPVVKKNGSM IPWTLRCNIE
     SFEQKSDDVD IDGMTDVEKE RIKKTPKQRI KIHSKEYLNV TVTKSCILLL YKLSEAFEKA
     AKQATPPQSR EFPGTSPYLI INETGLVVKV ANSDSMKVSE DNTDIDVSHG EPIDLDVIGW
     QDQTGLMLED DERAADLRLK LLETEREIAV LRAESRVIPL GKTSEGGRLW NMLVETVAEH
     NRKIIYLRSL VKFVNHMDTP FEVYSQRDNS LDLCGIAAKN SEPMIVPITY LYTVTGEFFI
     RPAGDQYDIS AESISWYDFK TDNRAWIRCE NTTASNKALF AELVVIPTAV FPEKGDLRSD
     VAYTVHIFPI LTFKNLLPFP IKIHDNQITI LEGGTDKSMN IYEGNSFRVS FEYNDETYEA
     DYTFEHTTEV EKVLYFTGKK DPTAEMYLGL HFGKEHFKQE VSIYAPFWIV NKTGKRIRYM
     DTSTLKHTKI CCFTRNKTKD RKRLSSLSQA DHVMEHKPDL NPVILSYPTS DPTLKSKIKF
     AVGDSNFSTE FPISNAGTAS RIMCTDEEGG KYDVTLEIVL SHNGLTKIVT FSPFFLLYND
     SLVDMEVREV GLDTWINVPA ESCTGLWPKQ TAKRMILNAR YATTEEESIA FPFTETFESF
     CRINNNYLGM YVTCSVTESS SVVHIEPYQL GMVPIVLMNA TTIPIKFKQK GCNDFYELKS
     NHMQPFTWTD VLSHERLLEW SSGDYSAFNG LHKSEMGDYP VPNSRRRNYW VSFLNGRQRI
     LLFSDDLEVV DKALKXNLND KMDMELEFTL HGMGISLVNN VLGQEIIYMS INNSKIVWER
     EYKSRFKCFP QGTIDALEVA YSKWLEKGKP NDEFHYNNET YNFTNMIYKK KTKEFKLARH
     FKPGVYIKIS SNNVKKLLNF QIFSVQIDNH LEACIFPLVL NVVPPPKSIQ KNSEPKPFID
     LAIYQIQPEG STIVQYQYFC LLLQEFAVQA DMGLLAAMMD FVAASSASKP YTRELYQKDI
     EYTKIKLSDK AVTTAASVQK CLFDDFSFSP LMIHLSFTLN NLSQSVDEDQ KQAANSQLEV
     LNVLLKSVGA SITNIANIQD VVLKLASFER KNAFMDFGKL SAEIQSHYMS QALKQFYVLV
     LGLDIIGNPF GLVRDLSSGV EDLFYQPITG FVQGPEEFAE GLAIGVSSAF SHTIGGVSGA
     ASRITGTLGK GVAALTLDDD YQRRRQEELN RRPQTFGQGM ARGVKGFGTG IIDGITGVAT
     KPIEGAKEGG FGGFAKGVGI GLVGVVTRPI SGTVDMASGT LNAIKVCATG NQFVEAARPM
     RYIHKDKVIR PYNHYESKGY RFFRQAEEGS YVETDTFIVH GVLEDKTILI VTDKRLFIVS
     KHCVTGALNT QWEMLFNEII EPQQVNDAIR IVPKVQKKGF LGLGKVKSKD IKLSREDDIK
     IVCSKLLKAY TIYNS
//