ID   A0A0N4ZWE3_PARTI        Unreviewed;       546 AA.
AC   A0A0N4ZWE3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Homeobox domain-containing protein {ECO:0000313|WBParaSite:PTRK_0001297400.1};
OS   Parastrongyloides trichosuri (Possum-specific nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Parastrongyloides.
OX   NCBI_TaxID=131310 {ECO:0000313|Proteomes:UP000038045, ECO:0000313|WBParaSite:PTRK_0001297400.1};
RN   [1] {ECO:0000313|WBParaSite:PTRK_0001297400.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC       ECO:0000256|RuleBase:RU000682}.
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DR   AlphaFoldDB; A0A0N4ZWE3; -.
DR   STRING; 131310.A0A0N4ZWE3; -.
DR   WBParaSite; PTRK_0001297400.1; PTRK_0001297400.1; PTRK_0001297400.
DR   Proteomes; UP000038045; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR031701; SIX1_SD.
DR   PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR   PANTHER; PTHR10390:SF33; PROTEIN OPTIX; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF16878; SIX1_SD; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682}.
FT   DOMAIN          193..253
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        195..254
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          240..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..441
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          465..546
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..302
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        419..439
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        465..479
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        480..495
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        496..546
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   546 AA;  61312 MW;  845CCA79ECEC0756 CRC64;
     MAAAGAEHLQ KLWMHLAMNS LPNFGNPSAT TNQSSIPPSL AGGLPNFGGL ASLFPVNIQP
     GSTPNSIQNP PSSASLSFNA EQVIKTCEQL EEAGEVESLA RYIWRLPPNI ANEISKNEAV
     LRAKALVYFH TGNFRELYAI LENHKFTSGN HGKLQAMWQE AHYQEAEKLR GRPLGPVDKY
     RVRKKFPMPR TIWDGEQKTH CFKERTRSLL REWYLQDPYP NPSKKKELAN ATGLTAMQVG
     NWFKNRRQRD RAAAAKNKQH GYGVDGLGGK NKSPGSDNSD SDMDDDLLNR SITSTPTNED
     ENNRDLMLGG DNKEDSSSPN NLLSKLTPTS LLSSMGPVFS GNHLQPSFEN IFSNFGVPPQ
     QQSNPMNGAL FPPSMEHFKM LMQNPLFQQI QQQMMFQQQQ AQQIQQQQLL HCLQKQQTSL
     NTPDKTSDSE STTSPIGEDL SVRGSLKRSK LSIDEILNIK RDKLEEDSEK VEENEPHNNN
     ESTSESNTSN DYLDPTSPEV KEEENLDNDK ELKEDGTVND ETKVKKEENV DKEEEGEIKK
     DDNENE
//