ID   A0A0N5A992_9BILA        Unreviewed;       327 AA.
AC   A0A0N5A992;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Homeobox domain-containing protein {ECO:0000313|WBParaSite:SMUV_0000066201-mRNA-1};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000066201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMUV_0000066201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC   -!- SIMILARITY: Belongs to the paired homeobox family.
CC       {ECO:0000256|ARBA:ARBA00005733}.
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DR   AlphaFoldDB; A0A0N5A992; -.
DR   STRING; 451379.A0A0N5A992; -.
DR   WBParaSite; SMUV_0000066201-mRNA-1; SMUV_0000066201-mRNA-1; SMUV_0000066201.
DR   Proteomes; UP000046393; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR001523; Paired_dom.
DR   InterPro; IPR043565; PAX_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR   PANTHER; PTHR45636:SF38; PROTEIN GOOSEBERRY-RELATED; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF00292; PAX; 1.
DR   PRINTS; PR00027; PAIREDBOX.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00351; PAX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 2.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS51057; PAIRED_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682}; Paired box {ECO:0000256|ARBA:ARBA00022724};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          14..141
FT                   /note="Paired"
FT                   /evidence="ECO:0000259|PROSITE:PS51057"
FT   DOMAIN          204..264
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        206..265
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          177..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        183..209
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   327 AA;  36575 MW;  3A6F7F883BDA20C9 CRC64;
     MADSKSLSFT NIMGQGRVNQ LGGVFINGRP LPHHIRLKII EMASKGIKPC HISRQLRVSH
     GAVSKILNRY AETGSIMPGQ IGGNPRSRLS VQAVEKQILA LKAEQPNLCA NELRSYLIER
     EICSSDNAPT VSSINRIFRH MKAKKLISET TKRIRKAKLN HSIENILGIS LAPSFTDDSK
     YESPETSSSE DESIRDKEDK STTERCRRNR TSFTAKQLEI LEAAFNANTY PDQEGREKIS
     HSTGLSEEKI MTWFSNRRAR CRKNLALGSG NPFGVQSIMA PIITPIPQQQ YVGLFPNQMA
     FFSCPPTSPN LKLQEPSMLL YPQFQAT
//