ID   A0A0N5AB03_9BILA        Unreviewed;       414 AA.
AC   A0A0N5AB03;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:SMUV_0000132901-mRNA-1};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000132901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMUV_0000132901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N5AB03; -.
DR   STRING; 451379.A0A0N5AB03; -.
DR   WBParaSite; SMUV_0000132901-mRNA-1; SMUV_0000132901-mRNA-1; SMUV_0000132901.
DR   Proteomes; UP000046393; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd20818; C1_Myosin-IX; 1.
DR   Gene3D; 3.30.60.20; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR046987; Myo9.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46184:SF5; HEAVY CHAIN, UNCONVENTIONAL MYOSIN; 1.
DR   PANTHER; PTHR46184; UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00109; C1; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          16..65
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   DOMAIN          83..273
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          345..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        349..369
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   414 AA;  47220 MW;  685A059BB5412C77 CRC64;
     MKTLKRDQFI GNLHNGHRFK SEIVHVPTYC EICNQFMWHA EKILICTGCR ISCHKKCHSK
     ITQSCTLNVQ KSINNSGGRF FGADLTTLVS EEQSIPVIIN KMFMIIELKA LFVEGIYRKS
     GSVAQVRSAR RAIETASKFD DLNLEDVPVH VICTLVKSFF RELPEPLITY ELYENFLNAS
     EVEESYERIR CLSVMVELLP KCNRCILDRL MYHLARVAFE EPVNKMGPNN LALIFAPCIL
     RSNQSAHAQE QLRDVNRQAI CVQALIEEKL KQYKSTLTQI VTLEGVGEKI TENLRRIEEH
     KNDSTASGEA YSSSKMETAR QLFIEQLDFL DTERDKLIQD LPPLAPVASS EDLSSSDEMS
     TSPLNTDKGQ QEEYALDFDA PPIFGRLNNP SSSRVRSRHT RPPTRQFRIS RISN
//