ID   A0A0N5AG45_9BILA        Unreviewed;       228 AA.
AC   A0A0N5AG45;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] {ECO:0000256|ARBA:ARBA00012596};
DE            EC=2.5.1.87 {ECO:0000256|ARBA:ARBA00012596};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000327501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMUV_0000327501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = di-
CC         trans,poly-cis-polyprenyl diphosphate + n diphosphate;
CC         Xref=Rhea:RHEA:53008, Rhea:RHEA-COMP:13431, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:128769, ChEBI:CHEBI:136960, ChEBI:CHEBI:175763;
CC         EC=2.5.1.87; Evidence={ECO:0000256|ARBA:ARBA00000976};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC       {ECO:0000256|ARBA:ARBA00004922}.
CC   -!- SIMILARITY: Belongs to the UPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00005432}.
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DR   AlphaFoldDB; A0A0N5AG45; -.
DR   STRING; 451379.A0A0N5AG45; -.
DR   WBParaSite; SMUV_0000327501-mRNA-1; SMUV_0000327501-mRNA-1; SMUV_0000327501.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000046393; Unplaced.
DR   GO; GO:1904423; C:dehydrodolichyl diphosphate synthase complex; IEA:InterPro.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045547; F:dehydrodolichyl diphosphate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019408; P:dolichol biosynthetic process; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.1180.10; Decaprenyl diphosphate synthase-like; 1.
DR   InterPro; IPR038887; Nus1/NgBR.
DR   InterPro; IPR001441; UPP_synth-like.
DR   InterPro; IPR036424; UPP_synth-like_sf.
DR   PANTHER; PTHR21528:SF0; DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1; 1.
DR   PANTHER; PTHR21528; UNCHARACTERIZED; 1.
DR   Pfam; PF01255; Prenyltransf; 1.
DR   SUPFAM; SSF64005; Undecaprenyl diphosphate synthase; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   228 AA;  26090 MW;  A49D17F998DA43C6 CRC64;
     MLWECLKVAY AFFEFFFKYI AKPSLLVEKV FSEQQDTPSR VPSHVAVVYT KKSEICVTAL
     ADLIVRCACA GVKKLSVYDP WSYLRSNKIV IEKLVKSKKP KLQRDIIDIH LSEPSESCKI
     RNDVLDVVLL GKESGKEALV RNCRKVCFQH SENAINTKLI SSYLAKDCLT EPDLLLKVGP
     LSSMAGYLPW ALRITEIVTV PHLLKHVSFN QFVSFIDTYY KRDRRLGR
//