ID A0A0N5AGB1_9BILA Unreviewed; 491 AA.
AC A0A0N5AGB1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
OS Syphacia muris.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000335101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMUV_0000335101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
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DR AlphaFoldDB; A0A0N5AGB1; -.
DR STRING; 451379.A0A0N5AGB1; -.
DR WBParaSite; SMUV_0000335101-mRNA-1; SMUV_0000335101-mRNA-1; SMUV_0000335101.
DR Proteomes; UP000046393; Unplaced.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45867:SF3; ACID PHOSPHATASE TYPE 7; 1.
DR PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 27..491
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5005733337"
FT DOMAIN 56..147
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 158..360
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 384..439
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 491 AA; 56980 MW; C444CA3A93C5ADFE CRC64;
MYARLVICRV LYSFLLLDLL RSYSFAIKNS STQPKLVPKG KKPELNANQG PYLGQPEQVA
LSYGGDASCM WITWITFDDT FKSLVEYGVD QLNLTAAGEH EYFVDDGELH LIRYVHRVKL
TGLKPATTYQ YHVGSEYGWS AIFRFTTFSE RLNGGYIFAV YGDLGNVNAR SLGKIQQYAQ
RHKIDMVLHI GDMAYNLDTD NGRFGDQFGR QIEPVAAYIP YMTVVGNHEN AQNFSHYVHR
YTMPNSEGNL YYSFNLGTAH FIAFSTEFYF YTNYGWEQIR NQWQWLMEDL KKANKDRKAH
PWIITMAHRP MYCSNFDDDD CTHYDSLIRT GLPMTHAYGL EKLFYTYGVD LMIWAHEHSY
ERLWPVYNRT VYNGTDSVYV DPPAPLHIIT GSAGCQENTD PFEEHPPPWS AFRSSNYGFT
TMQIFNATHI YFEQLTPSKT EPEDSFWFIK NSHGSYTKTH EKQMRKFGTY VPHDYCVDKN
SECEVFRKSV G
//
