ID   A0A0N5AXF5_9BILA        Unreviewed;       763 AA.
AC   A0A0N5AXF5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=CULLIN_2 domain-containing protein {ECO:0000313|WBParaSite:SMUV_0000963201-mRNA-1};
OS   Syphacia muris.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Oxyuridomorpha; Oxyuroidea; Oxyuridae; Syphacia.
OX   NCBI_TaxID=451379 {ECO:0000313|Proteomes:UP000046393, ECO:0000313|WBParaSite:SMUV_0000963201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMUV_0000963201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   AlphaFoldDB; A0A0N5AXF5; -.
DR   STRING; 451379.A0A0N5AXF5; -.
DR   WBParaSite; SMUV_0000963201-mRNA-1; SMUV_0000963201-mRNA-1; SMUV_0000963201.
DR   Proteomes; UP000046393; Unplaced.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF76; CULLIN-5; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
FT   DOMAIN          397..631
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   763 AA;  89189 MW;  55D965D617ED2F8D CRC64;
     MLGNENRYSF EKEWEEARET VVMLLNQQNV SKLRWQELFS IIHHIATWIE NGTELVRDKL
     DQEIHIYVVG ASERIQCHHE ENAMLRAYID EWQKFFSQTE HLPKPFSFIY SSHSNHSSLS
     RPNRNKNHSS EVTMIMLHEW NRIIFENVKD KLQAAAMRLI ESERNGRAFD PQLVIGVRQS
     YVSLNLDDVE PLAVYKSNFE HVYIETTKKY YKARAAQVLE ANGVQKYMVY ADTKLEEEKN
     RGLRYLESSS DSLKKVLDNC INVLVVQFQE QMLAECPAMI SNNQVEKLRM LYRLLNGTPE
     GIKSVLRYLG DYIKSEAMQD MKANASTITT DSEKYINQLL SMFSRFSRLV KDAFDNDSRF
     LTERDKAFQE VVNDTCIFKM EISNSRLKGT RMQAESRCPE LLASYCDLLL RKTSLSKRLS
     SDEIDSRLND VLLVLKYVNN KDVFMRFHKA HLARRLILEM SADQEKEEHM VTRMRDAGMP
     ADLVNKLFRM LQDIEINKDL NSTFKNSIGF NNNLMADTIS LKILNAGAWA RGNERVQLQV
     PRELEDVIPE VEEFYRKQHS GRKLQWLYHW SHGTITFTNA LGKFDLDVTT LQYSVLNCWN
     DRPYEKLSFE SIRIATQLPN AELTRTLFSL IGFPKLQLQV LCSDCETANP RSFTDSTLFW
     INQGFAIVKN NKKQNRGRLS LIGRLQLSTE SNNQAEHDDI IALRLMKMRK RCKSAQLQTE
     LIELLKHMFL PSKRLIKEQI EWLIENRFIS RDENDLNTFV YVS
//