ID   A0A0N5B3Q4_STREA        Unreviewed;       483 AA.
AC   A0A0N5B3Q4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Sodium channel protein Nach {ECO:0000313|WBParaSite:SPAL_0000070700.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000070700.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000070700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A0N5B3Q4; -.
DR   WBParaSite; SPAL_0000070700.1; SPAL_0000070700.1; SPAL_0000070700.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF232; DEGENERIN LIKE; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        50..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   483 AA;  56234 MW;  9C73B3AD11CE48BF CRC64;
     MEKKNVKDDN RYSFKSKREF LRKTLSEDYP GLDYLGIHNV LHAKAFWYKL LWLFVLLVCF
     ILGIYTVFAV IKEYHGKPSS TKISVHSVHE LLLPQITICP TNPMTLNLQK MANGLFIKNN
     ISTWNTSTVE DFANFMLLGS GFHKVNLDFL ESVNITEMTY LYDTFRNNVT VLEYFSEFFD
     TYGLQCSQFF KSCSLGSQKL DCCKIMTPTY TIRRGRCFRT IELKQKTFDE LGKLKLEIRK
     PKFMFNETKN VEIIAFVGEH KESLAPFPRY YISEGIWIKM RIFAKYINLI ERDGVCTDQV
     NSISKASCYL RDWMKTKVED PLNCTFPFVS LSKEVDLDGC RPDALAKVYR NIDDANYITH
     DCILPCDRWE YTVVNEAPKS LLNMDKPTKL DYSYRLDVSY NDLQYEVIEE VLTMSFTTLI
     ALVGGQFSLF LGSSLLNFIQ AIIMIIILSK RLIKVSRRKL QLMRRPQIST PECSITLKDI
     EKF
//