ID   A0A0N5B7H0_STREA        Unreviewed;       484 AA.
AC   A0A0N5B7H0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Acid-sensing ion channel 5 {ECO:0000313|WBParaSite:SPAL_0000199600.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000199600.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000199600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A0N5B7H0; -.
DR   STRING; 174720.A0A0N5B7H0; -.
DR   WBParaSite; SPAL_0000199600.1; SPAL_0000199600.1; SPAL_0000199600.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF232; DEGENERIN LIKE; 1.
DR   Pfam; PF00858; ASC; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        65..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        447..467
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   484 AA;  55676 MW;  6B5022225EEBC5EB CRC64;
     MHFLIKGKFI TNNNLSSFLF ICSKISLNCD GPRPHTKCRH CSNLWKSELH GLGLLISLKP
     GIGKILWFVV ILVGFLAAIY LTALVIEEYY SKKTATLIKI QRNKELLYPY VTLCPKSSDT
     FNITAVRKDI WSFKPALSKK TVDNLIIYAL AGSGIDNYGP LISNFNSADM IELEGLMNSW
     IKQKGSINNL YKFILEDVNF TCKEFLIQCY YGGDYLDCCS VFKPTYVLLR GRCYTLNNFY
     QRDPDEIGKI GLVIGSLPSA FITNETYQMQ LVVYNSNPGP DIGIFPRFYL NALDWNRFRF
     TQQQYDLLPA NVQCNSSPHY NGRSSCFIDH WFEENVYSKD KCVFWYMSYR SPNMTICNPT
     FVVKNYNDIV PVEIQSIPCL QSCKRHETSI ELISRPYNFK LTGIDKDTIP LFRIEMSYTI
     LQTELYKEVI TTTVPGFISQ MGGHSGLFLG FTIITALQFA VIIIKTVKKK YDILKNDDLR
     FIMW
//