ID   A0A0N5B7J5_STREA        Unreviewed;      1278 AA.
AC   A0A0N5B7J5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=5-oxoprolinase {ECO:0000313|WBParaSite:SPAL_0000202000.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000202000.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000202000.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
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DR   AlphaFoldDB; A0A0N5B7J5; -.
DR   STRING; 174720.A0A0N5B7J5; -.
DR   WBParaSite; SPAL_0000202000.1; SPAL_0000202000.1; SPAL_0000202000.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
FT   DOMAIN          15..219
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          243..539
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          560..727
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          753..1276
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
SQ   SEQUENCE   1278 AA;  139502 MW;  B850DEC12EFC4AC8 CRC64;
     MTVECKKKCI GKLGFAIDRG GTFTDVICCY PSGKIEKLKL LSEDPTKYKS APTEGIRRFL
     QKFTEKNIPI EEPLPTENIE WIRMGTTVAT NALLERKGQK CALLVSKGFK DILHIGNQTR
     PNLFDLNIIK PEVPCNKVVE VNERILLPID SVYKDVEYKI DGLYGSCGHL DGLIIESSIE
     TSNVEEQIKL LKEEGYTSLA VSFLNSYAYP GHERHAEAEA YRAGFEHVSV SHKVSNMAKF
     VPRTFTTVTD AYLTPIVKEY IESFKKNFID NLRGVNLEFM RSDGGLCAIN DFIGCRAILS
     GPAGGVVGVS ITAYNEKTKQ PVIGFDMGGT STDVSRYAGE FEHTLETQTA GVTIQVPQMD
     IHTVAAGGGS RLFFRDGRFI VGPESAGSDP GPVCYRKKGY LTITDANVVL KKIIPERFPK
     IFGPNGDEPL DYEASYNEFE KLTKTINSYL TDMGQPSLSI ENVAEGFVNV ANETMSRPIR
     TLTEGKGYNT AAHELCSFGG AGGQHCCAVA EKLGITKIKI SPHCGLLSAY GIGAADTVTD
     TIWPYNDDLL IGERKRQFLT KKIISMMKET KDNLLNNGFK NLDVHHKVEF YLRYHKTDST
     IPIVVDIAKT DVNGILKLEE LERAKEAFEM LHKKQFGFVH CDRKVIVKDI RVIASAKRFS
     YPKIERTNNN SSTNNYEYEE IVKCFFNGKW METKCLLLEK LTTGKVIDGP ALILDADSTV
     VVDPNCKGTI TYDGSIEIDV QDRGLKNIGV NLNPIHLSIF SHRLMSIAEQ MGKVLERTAI
     STNIKERLDF SCALFGPDGD LIANAPHIPV HLGGMQTAVK YLIKLKGPGG IKPGEAVLSN
     HPKEGGSHLP DLTVITPIYI SNQEIPDFYV ANRGHHSDIG GLVPGSMPPN STTIFEEGAV
     FKNAFTIVEN GIFLESKVIE ALNEPAKQPG CTGTRQLGDN LADLKAQIAA NQKGISLLTD
     LTNEYGLDVV KAYMKHITEN AEKCVRDYFK SLPNSTIKSK DMMDDGTVIN LSIQIDKNNG
     KAIFDFTGTG PQSKYNLNAP EGVVKAAIIY CIRCLVGRDI PLNQGCLNPI EITIPPGTIL
     TPSDDAAVVG GKAVVGGNVL TSQRICDVIL SAFDACAASH GCMNNITFGN KYMGGYYETI
     GGGSGAGDTF AGQSAVHTHM TNTRITDPEI VEARYPVIVR EFCIRKDSGG KGKHDGGNGI
     IRRLQFRAPM TLSVLTERRT TRPFGLCGGK PGKCGVNSII SLNGEKKNIG GKSTIEVSAG
     EMLEIKTPGG GGYGVPTI
//