ID   A0A0N5BJT9_STREA        Unreviewed;      1014 AA.
AC   A0A0N5BJT9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:SPAL_0000620800.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000620800.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000620800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N5BJT9; -.
DR   STRING; 174720.A0A0N5BJT9; -.
DR   WBParaSite; SPAL_0000620800.1; SPAL_0000620800.1; SPAL_0000620800.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.30.530.20; -; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR12659:SF7; CROSSVEINLESS C, ISOFORM C; 1.
DR   PANTHER; PTHR12659; RHO-TYPE GTPASE ACTIVATING PROTEIN; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS50848; START; 1.
PE   4: Predicted;
FT   DOMAIN          533..753
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   DOMAIN          812..988
FT                   /note="START"
FT                   /evidence="ECO:0000259|PROSITE:PS50848"
FT   REGION          129..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..246
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          305..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..149
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..224
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        305..328
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1014 AA;  115705 MW;  A224200F0AA1C35D CRC64;
     MNERKFHFYG TTNQQQNIKI VPFEYMLKGS PSSEECTNKK KNEKKIDVIY DDVPSTSSLL
     SISPTNNIKT PNEDKNFSSS INERKIEKFM SSMLINAKEL CSIDQYQDSV KESKDNSNLR
     YFNKNYNQTE MGNRHNKSGV EKNSEDKIKD DKIVDEKNVI TTSRKLNLGS PLSNSDSHII
     YQPTYNINNG KKSLITNSTT SGDSPTLSSS SSIVSTTDYH NYSREQANEP PKKIILKGNN
     THSIGDGKVE VSSNKLIPNN YNIIKIDGYS NQNLYNNNIQ VEKKNKKEKD NHYIKEGEYS
     QSSSILLQSS SLSSDHHQPT TNKDKNNSIS DKLIMKDKDK NFSSNLVKSS TIISVNPLRS
     LIVNDDGYYS HSPDPTKKYS NNRKNPSMTL KNSLTYHHSF FSPVKSNRSG YGSQLIDRQS
     SWLPNVTRIS TSIISDSSDD GGKLDETILD DDTHVHRNLL YQTAINIDFL VDSTSSCLFG
     LLDKHSTSRL NNTKKIGVLG SNIRRFFSSS KHTSKNGDIT FYRTSKVPSC FGMSLSDVQG
     YCEGEVLPKC IFEIMKFLLN HASTTDGIFR KSGVRSRIEK LKSQCIVKFP NERVFYKDNG
     ECLLTMTQVH DVADTMKQYF REIPGKLFSE KISDFLICIA NGLPSDKQIE ALRYVILLME
     DTNRYAALAL FSFLNRISSW ASENNMSAEN LAVCFTPSLF NLNTESDKGT NSMSNLRLKR
     RKTIAMPSEQ ELMEYQGAQK SLALLIKHYE HLFNLPTDLH RQLKVRSPFF NFGCYNEPTI
     NINNITDIDI KECQNQIRGL VYEIVNDYGL DWNTWIPDCC YRDIAIYRKP VERCKFHFIR
     ASFTVGVSPH EMWKVLSKNR KAWEKNVDYT SSVFVINNES DIQLISYKNY DERQEFSKKC
     LLFRTWKKDS PELRGGVVLI ERSVEDKEFT HSNGHNIFPE VTCSCFLIMP SGNGSSKVNY
     IHRADVKGRG DLYYSKVYPK VITQKMVNLK NYFNITSSAR NPSNGPVKGK ETSF
//