ID   A0A0N5BP30_STREA        Unreviewed;       900 AA.
AC   A0A0N5BP30;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:SPAL_0000765800.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000765800.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000765800.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A0N5BP30; -.
DR   WBParaSite; SPAL_0000765800.1; SPAL_0000765800.1; SPAL_0000765800.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF103; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        356..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        381..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        477..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        684..704
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        709..730
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        736..761
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        823..844
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        856..878
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          252..409
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   900 AA;  103546 MW;  C0893CD4C633AB04 CRC64;
     MRPLEKIFFQ YGIFISKYPG WFLIIPSLIT IITTFGFLKF HTQDDIWDIY APINALSRVE
     EGHLKEFEFP SGSHHYRIQI LIQHKNESEY IFNKRFLNEI EYLNKFVSDN VTISDGFRNY
     FYNQLCGVYC EESNDLFLSY LQAILETNDD TFNFKLSYPI GQALQKQIFL GYSLGFVNYT
     NINKNDINNF KLLILHFMVD QNLPNSKILT NELENKLINI FSLATKASKH LKYEVHSRRR
     ELEEQRKITL KSLPYLAITG GLLLLFMIVT LVDIPLYNSQ HVEAFFGVIS PLMAIITSFG
     ILAQCDFPFS NILTVVPFLV LTIGIDDAFL ILAGWRQGSS TLTFSDRMGE ALAKSGASVT
     VTSITDVLCF AVGLFSNIPV VQLFCLYTSV ALAIDFIYQI TFFTAIVVYC GKKQFKYKSE
     ERSKSIKSNN SSSSSQDGQI STHKGSFLEL LKRKPKKNDN KLTFFMKKFV VFLHWPITKY
     CTMVIFITHL VLTIYLCTKV TTEFDMENLY LKESPLTHIA RTLQKFVLEE SFVVNFGIDK
     TPDFYIPEIK SLFDEMLHNL ETLPKYSMGS IGTLVWTRDY DLLTQIMEEE EDLWSPATVM
     KNYNDFKLDK KFIKTKVNEK GEEYIHNFWW QITYHKMNNF MDVEELLKLR RGILMKYSNV
     FNISSHHPLE KVPTESAASA PINFIQTAIS AVLLMSLLVL LFVYDFGAII SVVLSILSIS
     GGTVAYLHVW DVHLDAVSLI SILLSIGFSV DYSAHICYHY FTHIEEDNSR KENKSQITTI
     SKDTNKRFNI PESYFINNGK NHLHNNSTTT TTYKKIEDTF TSVGWPVIQS GLSTVLGMIP
     LVFVQAYVVD VFWKTIVLVT ALGLFHALFL LPVLFLIVED ILKCTKSTKV RMIEMNENKH
//