ID   A0A0N5BSU5_STREA        Unreviewed;      1123 AA.
AC   A0A0N5BSU5;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:SPAL_0000893700.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0000893700.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0000893700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A0N5BSU5; -.
DR   WBParaSite; SPAL_0000893700.1; SPAL_0000893700.1; SPAL_0000893700.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF97; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        454..476
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..510
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        516..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        560..585
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        597..626
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        688..708
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        924..943
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        950..970
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        976..996
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1017..1044
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1056..1079
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          461..625
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          355..375
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1123 AA;  126864 MW;  3F5A1754A6549A31 CRC64;
     MKEGKSTSDG RDSPEPVQLA SEINENGVHT LCVGVTDRPA ISPNHSPKVP LKETLSNASS
     TFPLPPSHIG VTAKNAANKL SSAASQDPRR RVTGGRIFPE RRRGSLLVGQ RSLDLMAEKG
     NLEGNQRFVK FIIKQYKSWG YYVAEYDWQM VVVCIIISLL GMLKIFLTPQ LNDITGYSPY
     GARGRLEYST YQEFFSHDGL SIATYLYIEA KDKGTMLRKD LLKEAVDILD ITSGNITMYN
     SVSNKTYSFN EFCDSFCNIN EPVRHFYNGF MIQSEAVSSG EPLNDRIKLS YPTSVLFGRK
     VSLQPYFFGL EYDNETTTNA VIDDESSTTT DDILMNNTDT EDILTTTIPS TTSLKSTTTT
     KSLSKEIKSD GDKNRGKRFS EEELRKITNI KSLKIISFQF RAAHQKDWID SDVKAYEMAI
     VNYFKDIYKS DKLIVHAYSQ SYVETEMVRG GTSLLPYLTV GFIIMCTCSV VSVMIRAYYM
     HQCSPVKVML AVCACITPFM ACATALAILF LCQMRFASIL CVIPFLALSI GVDSSYLMIH
     EWQRVTKHCR EAPSRRNSTV CYRMAEVLSE VGPAIMISAL TNIFADLVGC FTGSPEITLL
     CLGNLTTMFV MFIYQMTFYA GLMCLVGKYE IKQERVERTQ IAKENRSHGV VGGRHNTLNR
     QNSKFYETTK HAVSESMQAY VNFVTHKIVA GLTILIYFVF LALSIWGITQ IRINLSTQKL
     FALDSPLIVL DDLRVKYVIP HYMQATIFVN KPGNLSNVNE MKKVNQLVRD FEMLNGSWQS
     TGTQYFMRDF IIFEKSFEDE VEDESEPTNF AIDGISQPST SMNDQEYAKF YKEEDLPTFI
     RWPEYDFWSG FIKLNNNTKT NHTGLEKFFF TTSFHGEENS IWVVRGETLR SWRNVVDKYK
     DIDAHVFHED GVFLDLIHNM PTDTWQSVVG TMVCMSFVCF IFLNSFFTVF MSSSCVLSIS
     VGILGILSWW NIDLDPITMA AMIISIGFSV DIPAHVSYHY YQACQQEGED STPEVRLANC
     LGSVAFPAIQ AGISTSFCVM SLIFPKLYMA EVFVKTMIIT VVLCNLHGLV FLPAFLTVFD
     RIISSLKVMK KKQQIGGGDK EVSEMKWHPK TMEGGNKGKI SNK
//