ID   A0A0N5BZ61_STREA        Unreviewed;       318 AA.
AC   A0A0N5BZ61;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein 1 {ECO:0000256|ARBA:ARBA00014856};
DE   AltName: Full=Endoribonuclease MBLAC1 {ECO:0000256|ARBA:ARBA00032988};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001105600.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001105600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end
CC         ribonucleotide-RNA + a 5'-end (5'-phospho)-ribonucleoside-RNA + H(+);
CC         Xref=Rhea:RHEA:68096, Rhea:RHEA-COMP:15179, Rhea:RHEA-COMP:17355,
CC         Rhea:RHEA-COMP:17428, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:74896, ChEBI:CHEBI:138282, ChEBI:CHEBI:173118;
CC         Evidence={ECO:0000256|ARBA:ARBA00029337};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:68097;
CC         Evidence={ECO:0000256|ARBA:ARBA00029337};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}.
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DR   AlphaFoldDB; A0A0N5BZ61; -.
DR   WBParaSite; SPAL_0001105600.1; SPAL_0001105600.1; SPAL_0001105600.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR039344; MBLAC1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR23200:SF48; METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR23200; UNCHARACTERIZED; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
FT   DOMAIN          125..180
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|Pfam:PF00753"
SQ   SEQUENCE   318 AA;  35859 MW;  4FE581B80B91FB7B CRC64;
     MKYIFYLFLS LNYYFTLSLF IQKYDKDSNP ANILSQSLLK PNMAFLPQVN EQRRRTKRSV
     SLPDDIKDFK FNTVYFPMPD PRQGPIDGPT VIPILYGNFS MIDGDMIKLS TTSILILDEN
     SKTYEKCYIL VDTGLSLFKN TITGGLAAHG VKLSDINKLI LTHTDVDNLG NINLFPDALI
     FSGNREIKRA SFKVNTEDGY EHSEYGMPTV KICDNTEIML TPGQSIDGLS IIVRNVSGYG
     DIGIVGNLFV SESDLTKPLL WQQFVKDANQ ATVWEASREQ ILCTVDFIAP GYGVMFKIPD
     DIKNQIKSKC NELKNSRI
//