ID   A0A0N5C0X1_STREA        Unreviewed;      1130 AA.
AC   A0A0N5C0X1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Tyrosine-protein phosphatase domain-containing protein {ECO:0000313|WBParaSite:SPAL_0001165000.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001165000.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001165000.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0N5C0X1; -.
DR   STRING; 174720.A0A0N5C0X1; -.
DR   WBParaSite; SPAL_0001165000.1; SPAL_0001165000.1; SPAL_0001165000.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd00047; PTPc; 2.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR46163:SF5; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR   PANTHER; PTHR46163; TYROSINE-PROTEIN PHOSPHATASE-RELATED; 1.
DR   Pfam; PF00102; Y_phosphatase; 2.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 2.
DR   SMART; SM00404; PTPc_motif; 2.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..1130
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005895216"
FT   TRANSMEM        465..493
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          503..780
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          869..1101
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          1020..1092
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
SQ   SEQUENCE   1130 AA;  131873 MW;  8C6D0339FFCF5EBA CRC64;
     MFLHLWILTG VFVSIQNQIY SNITFHTQHF PGIVKSTENK TFSLNLSANA ANGFIIVKCP
     YESYKPPGNV SDSFQIPSEL NTSQLITVNK DKQFNWMPLL KSLSESTIIE CGQYLEKING
     NPIPYNWTYN LNWNAYSNQS IPVVSEDMSS HRRPIPKNCD NNSTKILIFT KDKHGNITKV
     EIYGEISLFQ NQIFYYFSMN ENTTRVIKEP CAILKVKKPC PKIEITKQDI TLVDHGSIKI
     NVAKMKENKE KYNVKLSVGN DSNYYSEKTI SVSKLRYHKN GVDIIKNFTK PVAETLDIDV
     FDLYKITYNC QSEGNLTIIS QIYYFEPTNS DYKYQNDSII YNKDDLSVKP NCSRNRLTYG
     YLEAIVQNGV RINLTDLTLS SENVMSYNIN DKFIYLTNIK NDTTILECIY RTPSGEVTIS
     SSFSLRNKMN EQNSNGTKSD NITRISRNGS KSWYQSLVHK HGKSVAITII FAIILAIILV
     IIGLSILLYF FIIKDYIELS EVKEKYRNVY DFWYHLRKHS LEKYCENVNN IEYISEKLKS
     NKIAKKIEGG EECDIDINHI YDDTLIKSYD SIDKAFKAHY VFKDSFERTY IISDSPTKET
     RDHFWKMIFE ENVQSVIAII YKRIMDTNNH FSNKIYWPDN DCKYGNITVE LIEREQLDLV
     SITCHFFKMT NNNNITKTVR IYHFNDWPNH GIPPSELYIV NLYKTINALN SSGNVLVHAF
     QGTGSRVYMY TFFVCIYDTM LNNINISNPM EVIKEIRDKR FGGNLASYEY AYVINALVTI
     FFENKMLIDN SYRSRYFLRQ FDNYLSTFLK RENRMSRGYA QFLMFVNIID LGKLREIKTT
     FAGTGILSDS ILKEKCKRFY ALIEDKSIKK IRHRDIPCFD STLVDINEKN EKGFVHANTF
     IYKNIEGLER KLILCQAPVK ESFDDMFDMI YKHNVAVIII LLRPDEAPPD GDKWVPYLPT
     SNEILKTQKY VVKCKKYSED CMNMIFESEY TIEKSKEKPI TFRIFHYHGW PDKGVPSNHK
     DVYELIKKIQ SCDPKNYVAI NCSSGIGRSG TIAFILHLID TFSSYINFEP IERLRTLREN
     RYKSVQTFSQ FVFAILIVYE HFKDHIDNMD PRLYPNFVKL TQKVFKDDNF
//