ID   A0A0N5C312_STREA        Unreviewed;       411 AA.
AC   A0A0N5C312;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Major sperm protein {ECO:0000256|RuleBase:RU003425};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001236700.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001236700.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- FUNCTION: Central component in molecular interactions underlying sperm
CC       crawling. Forms an extensive filament system that extends from sperm
CC       villipoda, along the leading edge of the pseudopod.
CC       {ECO:0000256|RuleBase:RU003425}.
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DR   AlphaFoldDB; A0A0N5C312; -.
DR   STRING; 174720.A0A0N5C312; -.
DR   WBParaSite; SPAL_0001236700.1; SPAL_0001236700.1; SPAL_0001236700.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR008962; PapD-like_sf.
DR   PANTHER; PTHR21515:SF4; CYLICIN HOMOLOGUE-RELATED; 1.
DR   PANTHER; PTHR21515; MAJOR SPERM PROTEIN; 1.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SUPFAM; SSF49354; PapD-like; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|RuleBase:RU003425};
KW   Cytoskeleton {ECO:0000256|RuleBase:RU003425};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..411
FT                   /note="Major sperm protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005895309"
FT   DOMAIN          304..411
FT                   /note="MSP"
FT                   /evidence="ECO:0000259|PROSITE:PS50202"
FT   REGION          30..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..303
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   411 AA;  46432 MW;  5355FE3DE14E660F CRC64;
     MFLDICSNIT ILFIALCAFL GFIVPGCKGG DKKKACTDGK LKDARSNEIS KKKKTSKKVT
     EKKKIVDKKD AQPVDDEKEA ATKKVSANKD SEKKKAVSQN DRQKTVKKQV DEKKEENEGE
     KKETPKTEDN KKVSPKEVST KKEDKKTDDK NEGDKKGKEK KEKDEDKKDG DNKDGDKKEE
     DKKEGDKKTE DKKDEESKGD DTNVGTKKGE IKKESDRKEE TKKGESKKED TKKEESKKGE
     SKKEETKKED TKKEDTKKEE SKKEETKKGE SKKDDTKKEE SKKGDKKEDE NNNVDAKNDA
     ESNDIKLSHE KIVFEKAQGK AVLELENKSN VKRAIKIKCS DNNTYKVNPV FQYIEPGKKL
     NVEIIRSSTP NKVDKIVILN TPATLSGNTP QNEFKKNAKY PTSTIPLTVA S
//