ID A0A0N5C317_STREA Unreviewed; 442 AA.
AC A0A0N5C317;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial {ECO:0000256|ARBA:ARBA00017279};
DE AltName: Full=Complex I-42kD {ECO:0000256|ARBA:ARBA00032828};
DE AltName: Full=NADH-ubiquinone oxidoreductase 42 kDa subunit {ECO:0000256|ARBA:ARBA00032628};
OS Strongyloides papillosus (Intestinal threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001237200.1};
RN [1] {ECO:0000313|WBParaSite:SPAL_0001237200.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305}.
CC -!- SIMILARITY: Belongs to the complex I NDUFA10 subunit family.
CC {ECO:0000256|ARBA:ARBA00008606}.
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DR AlphaFoldDB; A0A0N5C317; -.
DR STRING; 174720.A0A0N5C317; -.
DR WBParaSite; SPAL_0001237200.1; SPAL_0001237200.1; SPAL_0001237200.
DR Proteomes; UP000046392; Unplaced.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:InterPro.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR015828; NDUFA10.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000543; NADH_UQ_42KD; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Respiratory chain {ECO:0000256|ARBA:ARBA00022660};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 82..320
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
SQ SEQUENCE 442 AA; 52043 MW; EDDE8BBC35749145 CRC64;
MLGSLKILQG GAVRLVAPAS SILKNGSSVQ PLLHARSIVI KSHLDLPENY PEPFPYKEEK
IDFFKSIFDR TKSRFHQNSR LIVVEGNEGC GKSQVAKELA DQFGMLYMPE FKMEEILIDR
YGNDLRDYYH LFPKRFRIPD EKMFYKNPMS DMTACMRERV FHCKFDQYLN ALAHILNTGQ
GVVLEGSPYS DFVYTNAMKA NNYIGIEFLK FYYYMRKSAL PELHFWPHLV VYLDTPVEKC
LENIRKTGDS DKIGTLNETY LRTIAASYKD SLREYQRYSK ILAYDWVKQG NTDVIVEDIE
RTDFDFHEWH TNEIFEQWHE QTDEANWANW RVHVTNKTVA RYLAFGGLPT HEVGEIYINP
RDVSHYVDVM KNEVLKSPYG YGFIKERGDS GETKNIDGFE HSLPEVWYDY FFKEAYYDKL
ITFESAFDPQ SKWYNPDYLH HH
//
