ID   A0A0N5C5D0_STREA        Unreviewed;       487 AA.
AC   A0A0N5C5D0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001315900.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001315900.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- FUNCTION: Sodium-phosphate symporter. {ECO:0000256|RuleBase:RU363058}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 Na(+)(out) + phosphate(out) = 2 Na(+)(in) + phosphate(in);
CC         Xref=Rhea:RHEA:71259, ChEBI:CHEBI:29101, ChEBI:CHEBI:43474;
CC         Evidence={ECO:0000256|ARBA:ARBA00035083};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU363058}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU363058}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. {ECO:0000256|ARBA:ARBA00009916,
CC       ECO:0000256|RuleBase:RU363058}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0N5C5D0; -.
DR   WBParaSite; SPAL_0001315900.1; SPAL_0001315900.1; SPAL_0001315900.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PHOSPHATE TRANSPORTER; 1.
DR   PANTHER; PTHR11101:SF80; SODIUM-DEPENDENT PHOSPHATE TRANSPORTER 2; 1.
DR   Pfam; PF01384; PHO4; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363058};
KW   Phosphate transport {ECO:0000256|ARBA:ARBA00022592,
KW   ECO:0000256|RuleBase:RU363058}; Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363058};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363058}.
FT   TRANSMEM        28..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        66..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        108..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        168..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        237..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        372..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
FT   TRANSMEM        461..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363058"
SQ   SEQUENCE   487 AA;  52551 MW;  34DD70DB9F214D4A CRC64;
     METSIPTTMA TALSSTVSGL DMFQSSHLWA LILGFVIAFI LAFAIGANDT ANAFGTSVGA
     KVLTLLQAYV LASIFESLGA VLLGYKVTDT MRKGVLDLEV YEGKPTELML GQLGVLTGCG
     VWILVATFFK LPVSTTHSIV GSTIGFSLVL RGSDGIRWMK MGKIISSWFV SPFLSGVVSL
     ILFLGIKYII LKGKNPLRNA FISLPFLNFA TLWLNSFATM YRGPSFFGID QLSAVSVIMY
     TFVFSASLSL LGVFTLTPFL KKKIDDLKNQ SQKADEKNLP LCSENTKFID NNLTSTTKNN
     KSLEGGESTE SMRECCDLEA INKVFSYLQV VTACFGGFAH GGNDVSNAIA PLVSIYAIWQ
     EASVEQSSQT PIYLLLFGAI GMCVGLWLLG HRVIHTVGED ITRITPVSGF AIEFGAAATV
     LFASKLGLPI SSTQCKIGSV IFVGFVQNHH SVHWKTFGGI ALSWLVTVPA AGIFSALVTY
     ALRMFVN
//