ID A0A0N5CA15_STREA Unreviewed; 1582 AA.
AC A0A0N5CA15;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
OS Strongyloides papillosus (Intestinal threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001474000.1};
RN [1] {ECO:0000313|WBParaSite:SPAL_0001474000.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
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DR STRING; 174720.A0A0N5CA15; -.
DR WBParaSite; SPAL_0001474000.1; SPAL_0001474000.1; SPAL_0001474000.
DR Proteomes; UP000046392; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17101; FERM_F1_PTPN13_like; 1.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.42.10; -; 3.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46900:SF2; -; 1.
DR PANTHER; PTHR46900; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF00595; PDZ; 3.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 3.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50106; PDZ; 3.
PE 4: Predicted;
FT DOMAIN 634..950
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 1091..1174
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1403..1481
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1491..1573
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 277..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1302..1334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1303..1323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1582 AA; 179185 MW; EEC7A1CB22A7E9D8 CRC64;
MTDAAKVSLS ELIEVRGAGL EVEELLDITL VASEYLVKKR PLPNCKAQLF GVDEFNILKD
GNIEISFIPA NQADDGIIPP EIKDSNNPGK VVGSNTDAAF VWCLGTLLMN SGAADCKDPN
LFSLLNLLTV TDVGTRPSLK KLSQMVKNRM ERGRNSKQNL QELYSEIMGD DDELNEMSSV
GDISDRDLFS DEDIDERDHD EDDESDSHLF DYTEDIKNSK SNKKPEVHKN NIEKVEISNS
PFNDNFFESR NSPKQNVKNF KLKGLEKTVI DPFDFVDKDK QNDHNMHTLS GRDPFGDIEK
DLSESIINSN EKSSSETNYG FSRCLSDDDD IVQANVPFET PSPVSSPLST TDDLGYESPK
SNTDSQNKND KIKLDTETTN PSLTSYDKNT SSNDSRDFKI EQHNDKEIKP IVPQRTLPPK
SNSFFDNNNV EEKENDNVRS KCNDSTSPFK TQSIEVPPVS ARTRSIDYYK SQHVDAEVVV
KKPELTSKNP FENEKIISGT VTSKKLSKYI EDDNKINEEE SIDDMFAKAR QQQKSGSSNT
TPSTFLHQQN GHIGNVEEND IVGTLRRRNS MALASIRKHN QKFNTMGYGS MRKKLNKTAA
VPEFIEKNSL PHIHLNAQLA KKKKILTLYR VENTDVRVKL LNGQYIDVKC KSDVKCDEIF
NLVVSHCNIH EYHFFGLAIQ KDNEFYFLDP KKKIEKYAPA GWKNEKKAMT RQPYILHMRF
MRYPPLLSYV KTDVTMHELY LQLRNDILTE KLQANETIVF QLASLALQAE FSDKPDVSVS
SPTDYFLLDH YLPKQYFAYE DNKRIALMLS EMHEQLKGMK CHEAEIRFIK ICQTLPEYGS
HFYRIFKSKP TPEMLANTPT RNVDAGLSHF IAIMLNGICI YEISNNKKNM VQEFLWKDTN
TLQFDRKRFV IVKSNNFGAQ HFVFYTDHYT KSSYFVRFAA VQHKFIIRVR QWQSTLNRKT
EENPGENGVD VSVPKEDDII ATTIGTHNKS NHQEVFNNNK FKTQQTLLHE IPEHQNFKDN
GSKHSSEVLS NHKSIWENEN NDNRKVEESI PTYNLTDGIK NNYHSNGEKI SRTPSENHPD
YLHENKGQEL SINLEKDPRA GLGLTLVDGK WNGVKGIFVK AVTLGGAGEK AGVCVGDKLV
SVNGISLFGK DRHDAVTYVK ESNIYVTLGV IRYDNLASRH GKGITTLGRP QRKDSNLDSL
SLSSNVIRNT TNISNDPVVL KDGITPPTKK KQTTLPVFHK RTRAVSDFGA KSDTLPMFNT
EDIINELQKN TKNPSRIDLH MDSSDEEFGA GEYQVPATSM YKYHDSDNDD DEENLDKFHN
HHHNHTNGLY NKHKKSNHID NDLFDTKSWS SNNVPRTAVR SLDIPSINEN EEDDNEEVCN
INLGNTHINY QEERGNENIK ELIIIIKRSP TGSLGLKIAT GIEGAYIKQV NAEPALSSGI
QANDKLISIN NVYVQGMTHS DIIGLLRDGG ENVAIKILRD LTENEEEEII TVNLIKRDTV
PLGLSLSKKT DSEGSFIRHI AEGSTAFLEK SLKIGDRIWQ VNDIFVGNET PNNVVTLLKT
SNDDLKITVK RKIGQSPGIN NF
//
