ID   A0A0N5CCI9_STREA        Unreviewed;       431 AA.
AC   A0A0N5CCI9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Acid sensing ion channel subunit family member 5 {ECO:0000313|WBParaSite:SPAL_0001559600.1};
OS   Strongyloides papillosus (Intestinal threadworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC   Strongyloides.
OX   NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001559600.1};
RN   [1] {ECO:0000313|WBParaSite:SPAL_0001559600.1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0N5CCI9; -.
DR   STRING; 174720.A0A0N5CCI9; -.
DR   WBParaSite; SPAL_0001559600.1; SPAL_0001559600.1; SPAL_0001559600.
DR   Proteomes; UP000046392; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        395..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   431 AA;  49943 MW;  9B14071565B97521 CRC64;
     MMTLTIIIVM QKIFGRKIET KVLTTRRVNE DFFPKISVCF NIHNKYDEDS IFDSDPEFKN
     EFYGKKFSTD MKTNSFHDPE MYVNNLQRNY QIHVKKLIKD QDILTNVSVL ECTYLGQNCN
     KAMFNNSYDD YGIGRCFSFI KKKLHFGAFS RVGKEFGLSV LLKNEISDIK NHFRKAYGYP
     PYLSIQYQIF NDRDNHQLST FHTNILPLGY EVNIPITITK EIKNKNTSNC LYYNTGDPNS
     LHTSGAYTYD SCYTSCLKKN QLAQCQSVMP FEPNMCSKEK PCTCNDLNCF NCLSDSLFPD
     NLNNGILHPE FKDKCSCPPP CETYTYITNP TYSKLHAKNM AAMLGITGSE EDLEDDISAN
     YVILNFFIKE HTVLTKKEEI VYRSANLFAD IGNSLSLLLG LGMINIIEIF FCLFLIIIDR
     IRYFIKFRHL Y
//