ID A0A0N5CEZ4_STREA Unreviewed; 889 AA.
AC A0A0N5CEZ4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Rho GTPase-activating protein 27 {ECO:0000313|WBParaSite:SPAL_0001643200.1};
OS Strongyloides papillosus (Intestinal threadworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae;
OC Strongyloides.
OX NCBI_TaxID=174720 {ECO:0000313|Proteomes:UP000046392, ECO:0000313|WBParaSite:SPAL_0001643200.1};
RN [1] {ECO:0000313|WBParaSite:SPAL_0001643200.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
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DR AlphaFoldDB; A0A0N5CEZ4; -.
DR STRING; 174720.A0A0N5CEZ4; -.
DR WBParaSite; SPAL_0001643200.1; SPAL_0001643200.1; SPAL_0001643200.
DR Proteomes; UP000046392; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR23176:SF129; RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
FT DOMAIN 193..226
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 425..539
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 660..880
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 826..847
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 889 AA; 100549 MW; 0D61D2018CDA6030 CRC64;
MSLTALSSMS ERITPTTSNN PRFHETIQES PLFKRMYQST EEDHGNTLDE NIIENDTSTD
EEQNNLKDFS FPPRHTESGT IEGKSYCKLP TTQSTIDEMA SSSTSSIYEP ILMGDVQMIS
TTTNPMTTSY YENVQSQNVF NNTSTFLTPS KYYGKSFQVD DEDEHVYANL SEITQIDRAP
DPPLPSEDTY PIRVLPTGWR EYKTPGGRSY FYHPVMQVCQ WKPPRTVASS FTTTFNNFQK
HQPSTPMLTS TIINNSEIHS IDNNIMSSST PPSQGCCSNG TENEVIKKGI IEHPELSESG
EYFSHPTGDQ KYYFGTDTFD SRKTSTETSG YVNHNPTIHE ASEMVNSSDS GILSGGQTST
VYNHHPKNSN IETGTKGRPY IPEISKDGHV RQTLEKLKSI DFSHPPILDT ITLPSPTLHH
STTTTSTMKG SIEKCKIIDF TSKSRKKEWV KNFMVLSKNH LLFYKDEKSA EKHGKHYEAP
LGVCDLKNAH ITFYEKRKNR PIIEIKTTDS EGLCVEYQIE GIDKHDTLNW YSILKSCTTA
LDSPTGFPSP TNNDSTNALQ RNSSFIASRN VPLINQQTPV MSKSTYLSSK SLKKGKSVSK
GDSMVSSMIE NIPCVDTVNG EPVPTKESII ERLLRFFRSR PSIESLRDRG IYRPEPVFGS
TLEIICKQEQ STIPKFLVVI TKIIEEKGLE TDGLYRVSGN LSTIQKIRCK VDQYNYDDIR
NEEDVHVLTG TLKLFFRELS EPLFPISMNK EFVNSIQTGN METRFVKIDE LLGKLPTVNR
HTLIHLLKHL QRVSNYSSKN RMQIHNLAIV FGPTLFGCDD RPIINKGKNT KESKTNSSSK
KKLQKKEISP PVQPNQNLAF KMIMYGQVLE FVLTKLDKFS IFKNYTSGM
//
