ID   A0A0N5CJI0_THECL        Unreviewed;      1052 AA.
AC   A0A0N5CJI0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Adenylyl cyclase-associated protein {ECO:0000313|WBParaSite:TCLT_0000018701-mRNA-1};
GN   ORFNames=TCLT_LOCUS188 {ECO:0000313|EMBL:VDM95053.1};
OS   Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX   NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000018701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TCLT_0000018701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM95053.1, ECO:0000313|Proteomes:UP000276776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CAP family. {ECO:0000256|ARBA:ARBA00007659}.
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DR   EMBL; UYYF01000011; VDM95053.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N5CJI0; -.
DR   STRING; 103827.A0A0N5CJI0; -.
DR   WBParaSite; TCLT_0000018701-mRNA-1; TCLT_0000018701-mRNA-1; TCLT_0000018701.
DR   OMA; FFQSPRP; -.
DR   Proteomes; UP000046394; Unplaced.
DR   Proteomes; UP000276776; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   Gene3D; 1.25.40.330; Adenylate cyclase-associated CAP, N-terminal domain; 1.
DR   InterPro; IPR001837; Adenylate_cyclase-assoc_CAP.
DR   InterPro; IPR013912; Adenylate_cyclase-assoc_CAP_C.
DR   InterPro; IPR017901; C-CAP_CF_C-like.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR036223; CAP_C_sf.
DR   InterPro; IPR028417; CAP_CS_C.
DR   InterPro; IPR036222; CAP_N_sf.
DR   InterPro; IPR006599; CARP_motif.
DR   InterPro; IPR003124; WH2_dom.
DR   PANTHER; PTHR10652; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR10652:SF0; ADENYLYL CYCLASE-ASSOCIATED PROTEIN; 1.
DR   Pfam; PF08603; CAP_C; 1.
DR   SMART; SM00673; CARP; 2.
DR   SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   SUPFAM; SSF101278; N-terminal domain of adenylylcyclase associated protein, CAP; 1.
DR   PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
DR   PROSITE; PS01089; CAP_2; 1.
DR   PROSITE; PS51082; WH2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000276776}.
FT   DOMAIN          827..848
FT                   /note="WH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51082"
FT   DOMAIN          896..1031
FT                   /note="C-CAP/cofactor C-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51329"
FT   REGION          776..825
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        792..811
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1052 AA;  117015 MW;  A7F51D41DE07CBE7 CRC64;
     MFFQSPRPFG QHSTSYRSVN KSVCTSTSMS NLHTDSVQNG RSSGFATNYA RMYESNHFGP
     SIRSRLNQSA VGLNRSEKSR IPNRRGGEVQ VTKKQVLEDH SGSADSTEVP GLVSSRRIYQ
     VHKAVTSKQN LPIREKTYEG DESNKRQEVI VPILKTSVFN RLHVPSQQPP AWGHQTDSQE
     FVYNVYTDRN VSSNQNDRFR SNSAIPFSEH LPKEASLDVL SKVNLKGRSS TQPSEMHEAL
     FEKHGRNATR ITSSEQQLHR EPVFYQQVEK AKNYTTLQHF VPASERPLRR RISDPNLLQI
     DESNAQANIA MFNVAKGVRA ELEQDPKFRE KANVLDNTPT TEQAKTLSPI VLRGSSKQSP
     SMKHMEDFFE KSIQEFRKVL DSEEEKVTPE KKAFNVEHVR SIFRVNNDND RSKLLITSAP
     LAAVSDVPVH SKRNTSKMEE IQKVESMTVQ SGSKGMLTVD SVVNSTEGST IQAGNKIGTD
     GNQKYSSSSS GPVLFVVGKP LTNFVEQETA HSTLQKGANS EKHFDSVKAL ARPDCHSIPF
     ARNGNSVKKK TAESMDGILP GILLKSGNHH RSGSESGVRA HKKVAFQCDP NAASSAVVTR
     NEALIEAPLS VVQYDDAVDE PLQRFLRLSS DLGSDLQAVG EKVLRIFTEH RNLLWLAAGQ
     KEPSAEELQA KLTPLAKSIE DLSTFKESKR NTPLFNHISA ASEGIQALGW LTVKSTPAPY
     IKDMTEAAMF FVNRVLKEHK DDKVHTEWAK SWSAVLNALQ KYVRQVHTTG LVWNSCPGAR
     PSTLKQGEKS ILQGPPPPPP PPPPPPPPDF RSSESSISIA SDKSTADRTA LFAEINAGEN
     ITKRLKKVTP DMQTHKNPAL RSQYEAVDKD VQKVKALSTV MSDTSISAKI ENEKSPRTWL
     ENGKQWNVEY YKDDKNVMVR TDHMKQTLYV FKCVNSVIQV KGKLNSITLD SCKKTSIVFE
     SLLSQIEVIN CQSVQLQALG SMPTLSIQKT DGCQVYLSKE AINAEIITSK SSEMNVLIPA
     AEDGDFIEFP VPEQFKTIYD GKKLQTMVSD IC
//