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Database: UniProt
Entry: A0A0N5CLA2_THECL
LinkDB: A0A0N5CLA2_THECL
Original site: A0A0N5CLA2_THECL 
ID   A0A0N5CLA2_THECL        Unreviewed;       457 AA.
AC   A0A0N5CLA2;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   16-OCT-2019, entry version 17.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:VDM96040.1, ECO:0000313|WBParaSite:TCLT_0000088201-mRNA-1};
GN   ORFNames=TCLT_LOCUS883 {ECO:0000313|EMBL:VDM96040.1};
OS   Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX   NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000088201-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000088201-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:TCLT_0000088201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:VDM96040.1, ECO:0000313|Proteomes:UP000276776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; UYYF01000083; VDM96040.1; -; Genomic_DNA.
DR   WBParaSite; TCLT_0000088201-mRNA-1; TCLT_0000088201-mRNA-1; TCLT_0000088201.
DR   OMA; GHNRNGQ; -.
DR   Proteomes; UP000046394; Genome Assembly.
DR   Proteomes; UP000276776; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000046394,
KW   ECO:0000313|Proteomes:UP000276776};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     72     93       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    145    170       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       35    175       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      182    355       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   457 AA;  52686 MW;  D7A4F3111F6D8FDC CRC64;
     MECEDALMSL DNRERSSRFF KTPRIGSRRV RNRLVQKGGI CNISLVNVPK QRRKYFSDIF
     TTVIEIRWRW TLLFFATSFI ASWTFFFTVY YFIIVTHGDF EHITDSSWIP CVMNANSKMN
     IFLFSFTTQT TIGYGFRYPT SECPLIVITM CLQFMIGVMC HTLMTGVIFA KLARPIKRAA
     TILFSKNAVI CMRDGKLCLL FRVGDMRKSS LAEAHVRLQM IKKCITYEGE LLPFHQFDMD
     VGYDTGLDRV FVIWPITICH EIDENSPLYE ISKESLCTDT FEIIAILEGV VESVGSTTQA
     RTSYLPNEIL WGKRFEKLVT YQRDNGEYKI DFEKFHNVYD VDIPVCSAKE LDRMRDLGLK
     PENAYQIATN LSDNLIESPI VAIHPKGSNP RLSVLLNKHD NGTIHNPDKV EMDDEDNDET
     IHVNVGLKHK RPLLVCVQSP DFSTRHVQSI RRGPDIF
//
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