ID A0A0N5CLB4_THECL Unreviewed; 1060 AA.
AC A0A0N5CLB4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=ANK_REP_REGION domain-containing protein {ECO:0000313|WBParaSite:TCLT_0000089501-mRNA-1};
GN ORFNames=TCLT_LOCUS896 {ECO:0000313|EMBL:VDM96059.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000089501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0000089501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM96059.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYF01000085; VDM96059.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N5CLB4; -.
DR STRING; 103827.A0A0N5CLB4; -.
DR WBParaSite; TCLT_0000089501-mRNA-1; TCLT_0000089501-mRNA-1; TCLT_0000089501.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR CDD; cd21930; IPD_PPP1R12; 1.
DR Gene3D; 6.10.140.390; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR031775; PRKG1_interact.
DR PANTHER; PTHR24179:SF21; MYOSIN BINDING SUBUNIT, ISOFORM O; 1.
DR PANTHER; PTHR24179; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF15898; PRKG1_interact; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000276776}.
FT REPEAT 100..132
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 133..165
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 226..258
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 259..291
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 911..1017
FT /note="cGMP-dependent protein kinase interacting"
FT /evidence="ECO:0000259|Pfam:PF15898"
FT DOMAIN 1031..1060
FT /note="cGMP-dependent protein kinase interacting"
FT /evidence="ECO:0000259|Pfam:PF15898"
FT REGION 358..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 909..936
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 366..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..718
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1060 AA; 118045 MW; 68D4A4015F07F39F CRC64;
MISGMVREDS DVALEASHFA FLQQNKNVLG SNVLWRRKEQ LEKWETSETN RLPSVRRLNR
ESKVKFTDAD IFLSACLSGD LEEVGTLLDN GADINTTTVD GLTALHQAVI DGKPEMVQFL
VDHGANLNAQ DNEGWTPLHA AACCGNIDLV EYLCARGADL SVTNSDKELA LDLAEEDDCR
MVLEEEHHRQ SIDPDECRNR EILLMRRDAE QWLKDGEIQD NPHFRTGATA LHVAAAKGYH
DVMQLLLKAG ANVNCRDRDG WTPLHAAAHW AEHEAAAILI QNGASFSELT NNVGVFANLV
FLLNPGLGSL GETVLNVADK KIIEYLEGMQ EQERSRLTSN NSVNVLIHAN IPLKRSSSTT
SVLRMSTEEK TKKTKLDEQD ENKELREGHY SFVIEDKSPS PSVEVRLPFP SKQQLHDNSE
SSTEEERYLL MKDPHLTLFL KFIIFSTSRT SSEEKTASTF ESKNSNTNRN LPSASQSVSL
PQFEQGKTKN LPPDDKLSRT TSVPPLPSLT LANELKSSPE GQRNPTSCSS STTISSSVSR
SPSTESNSST SLAQNHLRIK NHIPDKEFTT TKTTVSLEPS AQSNKTASIH QPAATSVPWM
SLYRSSVIKG PLHPAFAHFQ AAVRQAATGN KSQAVKNVCT VQATVPSLSR GTLATPPMEP
NLPNESEAER RSKAKRQRDS RRSTQGVTRE QLRVATTLAV RRNDKEKDKD KENETQVHEK
NSSTSPSLES STSNEVEKKV VEGRKDLETN SYCSLQTLPA VPRTTRRVTG PIRIDGLQAD
ETSDDSVQSS GGDRLSACVT TPSLPSADLS ELITATTSYN VRYSDLTSIA STQATLTNKL
RPFAQHEDDF YCMLSFVEGI LLIAFVSLII VNLQLSFVSF QTNSVHIGGT KSTTVPLQIQ
NNRTKCQEIV DYKALYEKEK QETEKLRRRI EELSIEKSNS ASKTSYLNRG LEGRLTSSSS
LSKSLPSSID SRERRSYEQR IAEMQYEIEE LKKLEKTNAS LRLENEALIR VLSKMSRQQS
TPTWPRYLFD FQQLEHLRAD NQKLKEENGA LIRVISKLSK
//
