ID   A0A0N5CM66_THECL        Unreviewed;      1429 AA.
AC   A0A0N5CM66;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Chorion peroxidase {ECO:0000313|WBParaSite:TCLT_0000123801-mRNA-1};
GN   ORFNames=TCLT_LOCUS1239 {ECO:0000313|EMBL:VDM96570.1};
OS   Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX   NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000123801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TCLT_0000123801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM96570.1, ECO:0000313|Proteomes:UP000276776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UYYF01000143; VDM96570.1; -; Genomic_DNA.
DR   STRING; 103827.A0A0N5CM66; -.
DR   WBParaSite; TCLT_0000123801-mRNA-1; TCLT_0000123801-mRNA-1; TCLT_0000123801.
DR   OMA; MYTIWMR; -.
DR   Proteomes; UP000046394; Unplaced.
DR   Proteomes; UP000276776; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   CDD; cd09823; peroxinectin_like; 2.
DR   Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 2.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR   PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR   PANTHER; PTHR11475:SF131; PROTEIN CBG17660; 1.
DR   Pfam; PF03098; An_peroxidase; 2.
DR   PRINTS; PR00457; ANPEROXIDASE.
DR   SUPFAM; SSF48113; Heme-dependent peroxidases; 2.
DR   PROSITE; PS50292; PEROXIDASE_3; 2.
PE   4: Predicted;
KW   Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276776}.
FT   BINDING         1111
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ   SEQUENCE   1429 AA;  161862 MW;  51DDE0CB412B44D5 CRC64;
     FVASITALDI QSSDIRWNTI NKIDRQAKEL SYLSLLSIVA SQKIHNSLPK SNQKLLGLAS
     TNLENTVLSS LCPVNFIKEC PPVTYRTYSG HCNNVNNPLW GVSRQPMQRL LPSAYADEIT
     QPRIATDGSS LPNARTISLD LITEPTDKHN LCSMMIAQWA MFIYEDLVHA GVTLILKILG
     NEAKVLSCCE QGHKHPECYA IEITNNDSFY PKSIKCLSYV RTATSPRKLC SLGPREQANQ
     ATSFLDASQI YGSITERSKK LRAYKNGLNN ILLPKTSDRT CGNINNLQPC FLAGGELTNL
     IPTHTAIHTL WLRQHNKIAK ELKAINAHWD DERLFHEARR IVIAQIQHIT YNEFLPIILS
     KNKLRQYGVK LQINGYDSDY NLKTDASVLN EYASAVGLFF YSLFPDFLTL YETDEGSGKS
     RKSWSTVFND PGLLYRDKLD SILRFLLREA IRKPGLHMNM PFKNEFLRGT ATFGVDLAAM
     IIQMGRDHGI PGYTAFRRAC GLPPVSNFTD LEGVLNTFDV DKLSKLYTHI DDVDLFVLGM
     AEKPELGALV GPTFACIIGR QFEKARRGDR FWYENFFAPS AFSLEQLNEI RKTTLARIVC
     DNANGIQKVQ QNVFTLADFY GNCPMNCSST IIDRIDLTQW TDQEPRLILP ITKATLEKAI
     RLGAEHAKRL NDAEAVRIKK QVNINASRNA AIFIHSKLMA PRQESLQISH RAAILRETTK
     VLLKGDGLNE DERLPLELDV ATLQKLLPEV DVSRFVGNIS YYLGTEKPSK EECLPQPLPC
     DHTTKYRTFS GWCNNLKFPH YGNAFAPMRR LLDPVYDDGF DSPRTLSRTK KKLPSARAVS
     NAIHSEAPAF HVKYTHMLMQ MGQIIDHDFA HSPVSRGSGN TIIDCSSCDS AKTVSVHCFP
     IPIERGDPYF PHIQNNGEPK CISFTRSLLG QLTLGYRNQL DQLTSFIDAS FIYGSTECEA
     NKLRLFSQGK LNFTDLGFNR EALPQGPQER DCRSTPQHPC FEAGDERSNE QPGLTVMHTL
     FLREHNRIAL SLSRINNFWS DEKIYLETRR IMGAKVQHIV FNEWLPVVLG CETVARYDLM
     PRKTGYYTGY DGRCDATMTQ EMATAAFRFG HTLIRNILPR MNAEYQEKTS GLDLKASFNN
     ETFYYTHESG HIESVLMGLL GSQSMDFDRH ISNAVRNHLF QHQNGPFTGM DLPALNIQRA
     RDHGVPPYNS YREMCGMRRA RNFDDLKDVM DEGTIVALKS VYDHVDDIDL FPGIMSEKPL
     VGALVGPMLA CIIAEQFQRL KRCDRFYYEN DNPTTKFTPD QLVEIRKTTL SKLICSNSQY
     ANHIQPNAFL MPDELTNAPM KCSELPDVDF YEWLDRQFCV VDHRVINLGK TKRIRPCITC
     TCTSEGPKCY SMVIENCESL LTEYLISEVI DTVCVIQCSS LINKRNERS
//