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Database: UniProt
Entry: A0A0N5CX21_THECL
LinkDB: A0A0N5CX21_THECL
Original site: A0A0N5CX21_THECL 
ID   A0A0N5CX21_THECL        Unreviewed;       345 AA.
AC   A0A0N5CX21;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   05-JUN-2019, entry version 16.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:VDN02091.1, ECO:0000313|WBParaSite:TCLT_0000492101-mRNA-1};
GN   ORFNames=TCLT_LOCUS4910 {ECO:0000313|EMBL:VDN02091.1};
OS   Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX   NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000492101-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000492101-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:TCLT_0000492101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:VDN02091.1, ECO:0000313|Proteomes:UP000276776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; UYYF01004310; VDN02091.1; -; Genomic_DNA.
DR   WBParaSite; TCLT_0000492101-mRNA-1; TCLT_0000492101-mRNA-1; TCLT_0000492101.
DR   OMA; KDMNVGY; -.
DR   Proteomes; UP000046394; Genome Assembly.
DR   Proteomes; UP000276776; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000046394,
KW   ECO:0000313|Proteomes:UP000276776};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     57     82       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    135    162       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    164       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      171    328       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   345 AA;  39555 MW;  8D80217D2FB89A5A CRC64;
     MDDNDNHEAL LSSPLLTNKP ICPRLVTKDG RSILRQVGVP HHYQSIYKNW FHLVIECSWH
     VILCVFASGF ILSWITFALI YYTSNVLSSE SHKKVENERC IANVYDLKSA FLFSLETQHT
     IGYGFRYMTD TCLPMLFVLS LQCVAGVFLQ TLLGGIVIAK VLRPKKRKQA LRFSQVAVIG
     PINETDRRPA LMIRVADVQN NLYIAEPHVR LYMAISRINK KGERELADFK DMNVGYDNGW
     DRQSPLFAIT PDSLHSAHFE LILIVEGIVE ATGMTFQART SFLANEILWG YRFCPMVVLN
     EKIGRYEIRY KLFDETESID EINFKMIDMN SENEYGSSQN ISGFI
//
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