ID   A0A0N5D0B2_THECL        Unreviewed;       680 AA.
AC   A0A0N5D0B2;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Lysosomal acid phosphatase {ECO:0000313|WBParaSite:TCLT_0000622701-mRNA-1};
GN   ORFNames=TCLT_LOCUS6216 {ECO:0000313|EMBL:VDN03547.1};
OS   Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX   NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000622701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TCLT_0000622701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDN03547.1, ECO:0000313|Proteomes:UP000276776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC         Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000032};
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC       {ECO:0000256|ARBA:ARBA00005375}.
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DR   EMBL; UYYF01004399; VDN03547.1; -; Genomic_DNA.
DR   STRING; 103827.A0A0N5D0B2; -.
DR   WBParaSite; TCLT_0000622701-mRNA-1; TCLT_0000622701-mRNA-1; TCLT_0000622701.
DR   Proteomes; UP000046394; Unplaced.
DR   Proteomes; UP000276776; Unassembled WGS sequence.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR11567:SF210; INTESTINAL ACID PHOSPHATASE; 1.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
DR   PROSITE; PS00778; HIS_ACID_PHOSPHAT_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000276776}.
SQ   SEQUENCE   680 AA;  76433 MW;  824D2406AC5C3E01 CRC64;
     MVAEASVNAT ISPEMYTLIS STSASPTTVT KINILPLPLL KSAITVNTIS KEHAETTAKN
     LQLVTTAVKQ SVTALHKAET LPRDQVQKAT ITEEFTVKAT TDEKPVIQSQ TEAVLSTTLT
     NAAVTEPTKI TVLQAPTSVT NIGLQTPLAS IRSMTVPEIS TTTIRTLANL ENMLATPTNI
     DIAVEGIMSE TDVVRATSSV MTAVSSQAQT IPSPSATTDT SVIPSLTTPT LSMTETTLNV
     LSSEIPSHLA KIFTKTTVIP TLLPSLPHLA VETMSVTEAT TTSKTNSKTS VTTLETLIPD
     EISNIRIIND SKMLERKQSE AELIFLYTIW RHGDRAPLSI YPTDPYREST WPNGLGELTE
     IGMRQLFKIG RRMKQQYINC TPSFLSKNYN HREIYLRSTN VNRSLVSAMA LAAGMFSNGI
     AGKDYPRMED EEEWPHGWIP IPIHTKDVKY DYSANPFRRC HRAQFLEQQG FELLMYISNV
     TGNRKLKPEQ NLYHVYDTLI VERFHNLIQP KWFTTQIEKE MKVLRMELRK YNELIRLRGG
     AILAEIINRL IKKWKCIKKA DRECFWYRKI KFYGLSAHDT TLAALLTALE ANVKDADING
     PQYGATATFE LYRVNNKPYI KFLYSNIYSD APRAMTHLVP ECSSTFDLCP LRKFVTGRRR
     FLPVNIKKEC NIKRNRIQRS
//