ID A0A0N5D2H1_THECL Unreviewed; 524 AA.
AC A0A0N5D2H1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=RUN domain-containing protein {ECO:0000313|WBParaSite:TCLT_0000708401-mRNA-1};
GN ORFNames=TCLT_LOCUS7073 {ECO:0000313|EMBL:VDN04494.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000708401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0000708401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN04494.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYYF01004472; VDN04494.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N5D2H1; -.
DR STRING; 103827.A0A0N5D2H1; -.
DR WBParaSite; TCLT_0000708401-mRNA-1; TCLT_0000708401-mRNA-1; TCLT_0000708401.
DR OMA; HMESHIN; -.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR CDD; cd17679; RUN_PLEKHM1; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR025258; RH_dom.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047326; RUN_PLEKHM1.
DR PANTHER; PTHR12326:SF12; PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1; 1.
DR PANTHER; PTHR12326; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF13901; RH_dom; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM01175; DUF4206; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 4: Predicted;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 33..167
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
SQ SEQUENCE 524 AA; 60408 MW; 69BAAF58A259D939 CRC64;
MNMTELKEVK ANLTSELAYV LKQATSEYPS GTAVSKESTQ ILCNTIEALF IHGLKAAFFL
KKQRSSKYPE PNFWPFVCKY THKAVLDQIA ASNQIKTEVG KSRAWIRILL NENVMDNYLV
VLSRDTSTLS KFYEKWAFLR DAERVNILSD YMKGLTRLTL EAPVNSYLLN TWTPTPLILS
GLMSGKPARC ESYFHIHNFF FVVYLYFLEL VSIYSHPSML NEGSMSLSVL DQVNSSLVSY
PVQESSSLSC GANQVAIFLE LDIYLSDEVL IEMLTVIPHE KGLDFQSFRC PSCRKSIGPT
FASYSKCSFD EKYYCVDCFD GAGESVIPSR LIHNWDKRSR RVCKNNMIFI ESIRDKAVLR
IDRINPQLYE HSHALNTVKF LREKLSLSAT YLLTCRKSVA EDLESRLWPK DYLYRDIHLY
SFSDLLTVLS GHMESHINHL LNFTIKHIQR CLLCAQKGFI CEICSSSQVI YPFQLEITTR
CLECFSVYHK NCVGQNRCPK CIRRERYSQQ RPIFASHCLL FDMD
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