ID A0A0N5D737_THECL Unreviewed; 369 AA.
AC A0A0N5D737;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=SH3 domain-containing GRB2-like protein {ECO:0000313|WBParaSite:TCLT_0000886801-mRNA-1};
GN ORFNames=TCLT_LOCUS8857 {ECO:0000313|EMBL:VDN06442.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000886801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0000886801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN06442.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR EMBL; UYYF01004693; VDN06442.1; -; Genomic_DNA.
DR STRING; 103827.A0A0N5D737; -.
DR WBParaSite; TCLT_0000886801-mRNA-1; TCLT_0000886801-mRNA-1; TCLT_0000886801.
DR OMA; REPSCKA; -.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07592; BAR_Endophilin_A; 1.
DR CDD; cd11803; SH3_Endophilin_A; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035824; Endophilin_A_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF30; ENDOPHILIN-A; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..227
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 309..368
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 257..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 369 AA; 41422 MW; C6C970914C57F7F3 CRC64;
MGAAEATKLD DQYNDMERKV DLTYELISAL IAGTHELLQP NPATRAKMAT MGALSRVRGT
SKAQPYPQTE GLLADTMQKY GTSLGTDSDL GKALIDASEA YRQLADIKYQ MEDNVKHNFL
DPLAHLQQTE IKEVNHHRTK LKGRRLDYDC KKRKQTRDEE LIQAEDKLEE SKQLSEQAMY
NLLSNDIEQV TQLCALIDAQ LDFHRQTTQV LERLKTQLME RVAEASTRPR VQHVIKPVLP
DRVPSIRSSV HIENSTSINN ANFQPSASSM YPQKLQTEDG DWGSNALKSL NSNTNLTGPD
GPPPSAPPAR KASCRALYDF EAQNEGELEF KEGDVIELIS QIDENWYEGS LSGRTGYFPI
SYVQVLVPL
//
