ID A0A0N5D8T1_THECL Unreviewed; 348 AA.
AC A0A0N5D8T1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=CaMBD domain-containing protein {ECO:0000313|WBParaSite:TCLT_0000952301-mRNA-1};
GN ORFNames=TCLT_LOCUS9512 {ECO:0000313|EMBL:VDN07146.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000952301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0000952301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN07146.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UYYF01004813; VDN07146.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N5D8T1; -.
DR STRING; 103827.A0A0N5D8T1; -.
DR WBParaSite; TCLT_0000952301-mRNA-1; TCLT_0000952301-mRNA-1; TCLT_0000952301.
DR OMA; WAIRACE; -.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR004178; CaM-bd_dom.
DR InterPro; IPR036122; CaM-bd_dom_sf.
DR InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR Pfam; PF02888; CaMBD; 1.
DR Pfam; PF03530; SK_channel; 1.
DR SMART; SM01053; CaMBD; 1.
DR SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 131..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 213..284
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000259|SMART:SM01053"
FT COILED 286..313
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 348 AA; 40011 MW; 89DD70F49FC181D8 CRC64;
MKTLIVLSTI ILVALVIKFH VHEVQLFMIA NSAEDWRIAI TWPRGLQIAL EIVACGLCPI
PIDISFHWST TDGKLPLDVL LSIPMFSRLY WLCRVMLLHS RLFTDASSRS IAGLNRVNCN
ARFILKTLMT LCPGTMLMVF TASLWIIAGW ILRLCERFII NLLDTHQNYF DSLWLIAITF
LSGTCTSSMV VAVIARKLEL SRAEKHVHNF MIDTQLTKQL KHTAANVLRE TWLIYKNRFL
VDKIEPAKIR MHQRKFLVAI YALTTSNTYE IVHDIQNTQE GLSVRITAME HQLAEITREL
HNLSELIRSK RNTGNISCTI SEGFVSHEIP LTDAVRRRRN VIEQQYLK
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