ID A0A0N5D9J6_THECL Unreviewed; 162 AA.
AC A0A0N5D9J6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Ion_trans_2 domain-containing protein {ECO:0000313|WBParaSite:TCLT_0000981001-mRNA-1};
GN ORFNames=TCLT_LOCUS9799 {ECO:0000313|EMBL:VDN07463.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0000981001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0000981001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN07463.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666}.
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DR EMBL; UYYF01004884; VDN07463.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N5D9J6; -.
DR STRING; 103827.A0A0N5D9J6; -.
DR WBParaSite; TCLT_0000981001-mRNA-1; TCLT_0000981001-mRNA-1; TCLT_0000981001.
DR OMA; CNCEVTE; -.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000276776};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..144
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 162 AA; 18224 MW; 9E6562394451B436 CRC64;
MNLEEAHLKK KLEKLNFLIF GNRQEMLDSR SFRSAGSERS DEMSLPSVRR TGFTYKREKM
PVSVGIITVI LFIAGGAILF AVWEDWNLFD GAYYSFITLS TIGFGDIVPG QSLGEGSQEK
LIVCALYLLF GMALIAMCFK LMQDDVVQKA RWLGQKIGIL EP
//
